A short course of antimicrobial therapy for asymptomatic bacteriuria is safe and effective before urologic procedures
Introduction: In the presence of asymptomatic bacteriuria (ASB) before the urological procedure, the duration of antimicrobial treatment is controversial. This study aims to evaluate whether a short course of antimicrobial therapy is safe and effective in cases with ASB before urological procedures...
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The Journal of Infection in Developing Countries
2021-05-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/14377 |
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| author | Murat Kutlu Merve Arslan Yusuf Ozlulerden Kevser Ozdemir Selda Sayin-Kutlu Zafer Aybek |
| author_facet | Murat Kutlu Merve Arslan Yusuf Ozlulerden Kevser Ozdemir Selda Sayin-Kutlu Zafer Aybek |
| author_sort | Murat Kutlu |
| collection | DOAJ |
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Introduction: In the presence of asymptomatic bacteriuria (ASB) before the urological procedure, the duration of antimicrobial treatment is controversial. This study aims to evaluate whether a short course of antimicrobial therapy is safe and effective in cases with ASB before urological procedures.
Methodology: We retrospectively reviewed adult patients who had ASB before undergoing several urological procedures between 2011 and 2019. The patients received a single dose of an appropriate parenteral antibiotic, determined by antimicrobial sensitivity testing, 30 to 60 minutes before the urological procedure. If a urinary catheter was placed post-procedure, a second dose was given.
Results: A total of 293 patients who had ASB before undergoing several urological procedures were included in the study. The total number of procedures was 328. Female/male ratio was 92 (31.4%)/201 (68.6%). The mean age was 63.7 ± 14.9 years. The most common isolated microorganisms were Escherichia coli (155 [47%]), Klebsiella pneumoniae (38 [11.6%]), and Pseudomonas aeruginosa (28 [8.5%]). The most common antimicrobial used was ertapenem. A second dose antimicrobial was given for 290 procedures due to a urinary catheter after a urological procedure. The mean hospitalization time was 3.97 ± 3.42 days. None of the patients developed infectious complications.
Conclusions: This study has demonstrated that a single dose of parenteral antimicrobial drug administered 30-60 minutes before the urologic procedures and a second dose in the presence of a post-procedure catheter, was adequate to prevent post-procedure septicemia and urinary tract infection.
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| format | Article |
| id | doaj-art-0b6e24eac2a94fae911e45349a07ce2c |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2021-05-01 |
| publisher | The Journal of Infection in Developing Countries |
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| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-0b6e24eac2a94fae911e45349a07ce2c2025-08-20T02:16:14ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802021-05-01150510.3855/jidc.14377A short course of antimicrobial therapy for asymptomatic bacteriuria is safe and effective before urologic proceduresMurat Kutlu0Merve Arslan1Yusuf Ozlulerden2Kevser Ozdemir3Selda Sayin-Kutlu4Zafer Aybek5Department of Infectious Diseases and Clinical Microbiology, Pamukkale University School of Medicine, Denizli, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, Pamukkale University School of Medicine, Denizli, TurkeyDepartment of Urology, Pamukkale University School of Medicine, Denizli, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, Pamukkale University School of Medicine, Denizli, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, Pamukkale University School of Medicine, Denizli, TurkeyDepartment of Urology, Pamukkale University School of Medicine, Denizli, Turkey Introduction: In the presence of asymptomatic bacteriuria (ASB) before the urological procedure, the duration of antimicrobial treatment is controversial. This study aims to evaluate whether a short course of antimicrobial therapy is safe and effective in cases with ASB before urological procedures. Methodology: We retrospectively reviewed adult patients who had ASB before undergoing several urological procedures between 2011 and 2019. The patients received a single dose of an appropriate parenteral antibiotic, determined by antimicrobial sensitivity testing, 30 to 60 minutes before the urological procedure. If a urinary catheter was placed post-procedure, a second dose was given. Results: A total of 293 patients who had ASB before undergoing several urological procedures were included in the study. The total number of procedures was 328. Female/male ratio was 92 (31.4%)/201 (68.6%). The mean age was 63.7 ± 14.9 years. The most common isolated microorganisms were Escherichia coli (155 [47%]), Klebsiella pneumoniae (38 [11.6%]), and Pseudomonas aeruginosa (28 [8.5%]). The most common antimicrobial used was ertapenem. A second dose antimicrobial was given for 290 procedures due to a urinary catheter after a urological procedure. The mean hospitalization time was 3.97 ± 3.42 days. None of the patients developed infectious complications. Conclusions: This study has demonstrated that a single dose of parenteral antimicrobial drug administered 30-60 minutes before the urologic procedures and a second dose in the presence of a post-procedure catheter, was adequate to prevent post-procedure septicemia and urinary tract infection. https://jidc.org/index.php/journal/article/view/14377Antimicrobialasymptomatic bacteriuriainfectious complicationsurological procedures |
| spellingShingle | Murat Kutlu Merve Arslan Yusuf Ozlulerden Kevser Ozdemir Selda Sayin-Kutlu Zafer Aybek A short course of antimicrobial therapy for asymptomatic bacteriuria is safe and effective before urologic procedures Journal of Infection in Developing Countries Antimicrobial asymptomatic bacteriuria infectious complications urological procedures |
| title | A short course of antimicrobial therapy for asymptomatic bacteriuria is safe and effective before urologic procedures |
| title_full | A short course of antimicrobial therapy for asymptomatic bacteriuria is safe and effective before urologic procedures |
| title_fullStr | A short course of antimicrobial therapy for asymptomatic bacteriuria is safe and effective before urologic procedures |
| title_full_unstemmed | A short course of antimicrobial therapy for asymptomatic bacteriuria is safe and effective before urologic procedures |
| title_short | A short course of antimicrobial therapy for asymptomatic bacteriuria is safe and effective before urologic procedures |
| title_sort | short course of antimicrobial therapy for asymptomatic bacteriuria is safe and effective before urologic procedures |
| topic | Antimicrobial asymptomatic bacteriuria infectious complications urological procedures |
| url | https://jidc.org/index.php/journal/article/view/14377 |
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