Maternal Age at Delivery Is Associated with an Epigenetic Signature in Both Newborns and Adults.

Maternal Age at Delivery Is Associated with an Epigenetic Signature in Both Newborns and Adults.

Offspring of older mothers are at increased risk of adverse birth outcomes, childhood cancers, type 1 diabetes, and neurodevelopmental disorders. The underlying biologic mechanisms for most of these associations remain obscure. One possibility is that maternal aging may produce lasting changes in th...

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Main Authors: Christina A Markunas, Allen J Wilcox, Zongli Xu, Bonnie R Joubert, Sophia Harlid, Vijayalakshmi Panduri, Siri E Håberg, Wenche Nystad, Stephanie J London, Dale P Sandler, Rolv T Lie, Paul A Wade, Jack A Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0156361&type=printable
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