Chemistry and Biological Activities of Flavonoids: An Overview
There has been increasing interest in the research on flavonoids from plant sources because of their versatile health benefits reported in various epidemiological studies. Since flavonoids are directly associated with human dietary ingredients and health, there is need to evaluate structure and func...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/162750 |
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| author | Shashank Kumar Abhay K. Pandey |
| author_facet | Shashank Kumar Abhay K. Pandey |
| author_sort | Shashank Kumar |
| collection | DOAJ |
| description | There has been increasing interest in the research on flavonoids from plant sources because of their versatile health benefits reported in various epidemiological studies. Since flavonoids are directly associated with human dietary ingredients and health, there is need to evaluate structure and function relationship. The bioavailability, metabolism, and biological activity of flavonoids depend upon the configuration, total number of hydroxyl groups, and substitution of functional groups about their nuclear structure. Fruits and vegetables are the main dietary sources of flavonoids for humans, along with tea and wine. Most recent researches have focused on the health aspects of flavonoids for humans. Many flavonoids are shown to have antioxidative activity, free radical scavenging capacity, coronary heart disease prevention, hepatoprotective, anti-inflammatory, and anticancer activities, while some flavonoids exhibit potential antiviral activities. In plant systems, flavonoids help in combating oxidative stress and act as growth regulators. For pharmaceutical purposes cost-effective bulk production of different types of flavonoids has been made possible with the help of microbial biotechnology. This review highlights the structural features of flavonoids, their beneficial roles in human health, and significance in plants as well as their microbial production. |
| format | Article |
| id | doaj-art-0b6b643bd0464a3097036f31024ef523 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-0b6b643bd0464a3097036f31024ef5232025-02-03T05:48:18ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/162750162750Chemistry and Biological Activities of Flavonoids: An OverviewShashank Kumar0Abhay K. Pandey1Department of Biochemistry, University of Allahabad, Allahabad 211002, IndiaDepartment of Biochemistry, University of Allahabad, Allahabad 211002, IndiaThere has been increasing interest in the research on flavonoids from plant sources because of their versatile health benefits reported in various epidemiological studies. Since flavonoids are directly associated with human dietary ingredients and health, there is need to evaluate structure and function relationship. The bioavailability, metabolism, and biological activity of flavonoids depend upon the configuration, total number of hydroxyl groups, and substitution of functional groups about their nuclear structure. Fruits and vegetables are the main dietary sources of flavonoids for humans, along with tea and wine. Most recent researches have focused on the health aspects of flavonoids for humans. Many flavonoids are shown to have antioxidative activity, free radical scavenging capacity, coronary heart disease prevention, hepatoprotective, anti-inflammatory, and anticancer activities, while some flavonoids exhibit potential antiviral activities. In plant systems, flavonoids help in combating oxidative stress and act as growth regulators. For pharmaceutical purposes cost-effective bulk production of different types of flavonoids has been made possible with the help of microbial biotechnology. This review highlights the structural features of flavonoids, their beneficial roles in human health, and significance in plants as well as their microbial production.http://dx.doi.org/10.1155/2013/162750 |
| spellingShingle | Shashank Kumar Abhay K. Pandey Chemistry and Biological Activities of Flavonoids: An Overview The Scientific World Journal |
| title | Chemistry and Biological Activities of Flavonoids: An Overview |
| title_full | Chemistry and Biological Activities of Flavonoids: An Overview |
| title_fullStr | Chemistry and Biological Activities of Flavonoids: An Overview |
| title_full_unstemmed | Chemistry and Biological Activities of Flavonoids: An Overview |
| title_short | Chemistry and Biological Activities of Flavonoids: An Overview |
| title_sort | chemistry and biological activities of flavonoids an overview |
| url | http://dx.doi.org/10.1155/2013/162750 |
| work_keys_str_mv | AT shashankkumar chemistryandbiologicalactivitiesofflavonoidsanoverview AT abhaykpandey chemistryandbiologicalactivitiesofflavonoidsanoverview |