ATP-Binding Cassette and Solute Carrier Transporters: Understanding Their Mechanisms and Drug Modulation Through Structural and Modeling Approaches

ATP-Binding Cassette and Solute Carrier Transporters: Understanding Their Mechanisms and Drug Modulation Through Structural and Modeling Approaches

The ATP-binding cassette (ABC) and solute carrier (SLC) transporters play pivotal roles in cellular transport mechanisms, influencing a wide range of physiological processes and impacting various medical conditions. Recent advancements in structural biology and computational modeling have provided s...

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Bibliographic Details
Main Authors: Ahmad Elbahnsi, Balint Dudas, Isabelle Callebaut, Alexandre Hinzpeter, Maria A. Miteva
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
SLC transporters
ABC transporters
cryo-electron microscopy
artificial intelligence modeling
molecular docking
molecular dynamics
Online Access:https://www.mdpi.com/1424-8247/17/12/1602
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