Efficacy and Safety Assessment of Antifungal Prophylaxis with Posaconazole Using Therapeutic Drug Monitoring in Pediatric Patients with Oncohematological Disorders—A Single-Centre Study

Efficacy and Safety Assessment of Antifungal Prophylaxis with Posaconazole Using Therapeutic Drug Monitoring in Pediatric Patients with Oncohematological Disorders—A Single-Centre Study

Introduction: Posaconazole is recommended for prophylaxis in pediatric immunocompromised patients. Due to its variability in bioavailability and drug-to-drug interactions, EBMT recommends regimens based on therapeutic drug monitoring (TDM). Materials and methods: In total, 171 oncohematological pedi...

Full description

Saved in:

Bibliographic Details
Main Authors:	Karolina Liszka, Paweł Marschollek, Dawid Przystupski, Jowita Frączkiewicz, Monika Mielcarek-Siedziuk, Igor Olejnik, Zuzanna Gamrot, Natalia Haze, Agnieszka Kwella, Paulina Zalewska, Matylda Resztak, Marek Ussowicz, Krzysztof Kałwak
Format:	Article
Language:	English
Published:	MDPI AG 2025-01-01
Series:	Journal of Fungi
Subjects:	posaconazole therapeutic drug monitoring (TDM) antifungal prophylaxis
Online Access:	https://www.mdpi.com/2309-608X/11/1/38
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

A post-marketing pharmacovigilance study of triazole antifungals: adverse event data mining and analysis based on the FDA adverse event reporting system database
by: Yalan Tian, et al.
Published: (2025-01-01)

High-resolution hybrid TDM-CDM MIMO automotive radar
by: Zakaria Benyahia, et al.
Published: (2025-03-01)

Prophylactic analgesic effect of paracetamol and ibuprofen in the extraction of teeth in children
by: Mery Cecilia Paccini Torres, et al.
Published: (2019-07-01)

New perspectives in the management of acute pancreatitis – focus on antibiotic prophylaxis, management of necrosis and COVID-19 implications
by: Aleksandra Woźniak, et al.
Published: (2025-02-01)

Consultations for HIV post-exposure prophylaxis before and after health insurance coverage of pre-exposure prophylaxis to a university-based emergency department in Germany
by: Lennert Böhm, et al.
Published: (2023-12-01)

Therapeutic Drug Monitoring-Guided Linezolid Therapy for the Treatment of Multiple Staphylococcal Brain Abscesses in a 3-Month-Old Infant
by: Anna Cascone, et al.
Published: (2024-12-01)

Escherichia coli in the T11-12 Thoracic Vertebrae: A Case Report
by: Weng D, et al.
Published: (2025-02-01)

Usefulness of a TDM-Guided Approach for Optimizing Teicoplanin Exposure in the Treatment of Secondary Bloodstream Infections Caused by Glycopeptide-Susceptible <i>Enterococcus faecium</i>
by: Milo Gatti, et al.
Published: (2025-01-01)

Modern aspects of diagnostics and treatment of <i>H. pylori</i> infection from standpoint of stomach cancer prophylaxis
by: A. A. Sheptulin, et al.
Published: (2015-03-01)

Colorectal cancer: state-of-the-art
by: Ya. S. Tsimmerman
Published: (2012-07-01)

A persona-based exploration of rabies post-exposure prophylaxis seeking behavior and its implication for communication strategic planning: Evidence from Thailand
by: Jitjayang Yamabhai, et al.
Published: (2025-06-01)

No Emergence of Colistin Resistance in the Respiratory Tract of Lung Transplant Patients Treated With Inhaled Colistin
by: Nathalie Grall, et al.
Published: (2025-01-01)

The importance of dietary magnesium sulphate for prophylaxis of parturient paresis in cow with high milk production
by: M. Ali Bostancı, et al.

Living, Caring, Learning - Changing mindsets and enabling goals for people with haemophilia
by: Cruickshank Anne-Louise
Published: (2024-02-01)

Comparison of two bolus doses of dexmedetomidine for prophylaxis against postoperative nausea and vomiting in highly susceptible patients: A randomized controlled trial
by: Maha Mohamed Ismail Youssef, et al.
Published: (2024-04-01)

Human Immunodeficiency Virus Preexposure Prophylaxis Awareness and Acceptability among Men Who Have Sex with Men and Transgender Persons in India: Systematic Review and Meta-analysis
by: Adhish Kumar Sethi, et al.
Published: (2024-04-01)

The impact of organised educational campaigns on understanding of needle sticks injuries and related post-exposure HIV/AIDS prophylaxis
by: Ram Kumar Garg, et al.
Published: (2025-01-01)

Topical Rifamycin Prophylaxis in Gynecological and Obstetric Surgery
by: Nahit Ata, et al.
Published: (2022-03-01)

Prophylactic use of recombinant ADAMTS-13 during pregnancy for congenital thrombotic thrombocytopenic purpura
by: Éloïse Colliou, et al.
Published: (2025-01-01)

Fosaprepitant as combination therapy to prevent chemotherapy-induced vomiting in children: a meta-analysis
by: Yanshuo Shi, et al.
Published: (2025-01-01)

Long-term Conservative Follow-up in Children with High-grade Vesicoureteral Reflux and an Abnormal Dimercaptosuccinic Acid Scan
by: Pankaj V Deshpande
Published: (2024-03-01)

Isolation and study of biological properties of <i>Bordetella bronchiseptica</i>-specific bacteriophages
by: T. A. Kochetova, et al.
Published: (2022-09-01)

Effectiveness of aspirin in preventing deep vein thrombosis following proximal femoral fracture surgery in Japan
by: Takao Ohmori, et al.
Published: (2025-02-01)

Antibiotic-associated diarrhea: state-of-the-art
by: D. V. Piliev, et al.
Published: (2014-11-01)

Knowledge, attitudes and practices of oral HIV pre-exposure prophylaxis (PrEP) among healthcare workers in the Ekurhuleni District, South Africa
by: E Mahlare, et al.
Published: (2023-12-01)

Management approach to patients with premalignant lesions of the stomach
by: V. V. Tsukanov, et al.
Published: (2013-07-01)

The importance of environmental education in preventative healthcare
by: Ryszard Kowalski, et al.
Published: (2014-12-01)

A global review of national guidelines of post‐exposure prophylaxis for the prevention of HIV
by: Marcus Maisano, et al.
Published: (2025-01-01)

Posaconazole: A New Agent for the Prevention and Management of Severe, Refractory or Invasive Fungal Infections
by: Andrea V Page, et al.
Published: (2008-01-01)

High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Posaconazole and Vincristine in Rat Plasma
by: Hadeel A. Khalil, et al.
Published: (2015-01-01)

Comparing Fluconazole and Nystatin as Antifungal Prophylactics in Very Low Birth Weight Infants: A Randomized Clinical Trial
by: Leila Asgarzadeh, et al.
Published: (2024-07-01)

Perspectives and experiences regarding pre-exposure prophylaxis (PrEP) in a community sample of Veterans with unhealthy alcohol use: overall and across sexual orientation and gender identity
by: Olivia V. Fletcher, et al.
Published: (2025-01-01)

The latest therapeutic reports on short-term and long-term prophylaxis in the treatment of hereditary angioedema
by: Maciej Kozłowski, et al.
Published: (2024-02-01)

A prediction risk score for HIV among adolescent girls and young women in South Africa: identifying those in need of HIV pre-exposure prophylaxis
by: Reuben Christopher Moyo, et al.
Published: (2023-12-01)

Impact of invasive infections on clinical outcomes in acute pancreatitis: early predictive factors and implications for prophylactic anti-infective therapy
by: Fabienne Bender, et al.
Published: (2025-01-01)

Personality traits of women with hereditary risk for breast/ovarian cancer versus obstetric history and cancer preventive behaviors
by: Joanna Żurawska, et al.
Published: (2025-01-01)

Engaging the private sector as part of HIV pre-exposure prophylaxis service delivery in Vietnam: a comparative analysis of uptake, persistence and HIV seroconversion from 2018 to 2023
by: Bao Ngoc Vu, et al.
Published: (2025-01-01)

Successful Use of Posaconazole to Treat Invasive Cutaneous Fungal Infection in a Liver Transplant Patient on Sirolimus
by: Randah Dahlan, et al.
Published: (2012-01-01)

Acute Infusion-Related Side Effects of Amphotericin B Lipid Complex (ABLC) in Oncohematological Patients: Real-World Data from Brazilian Reference Centers
by: Francelise Bridi Cavassin, et al.
Published: (2024-11-01)

A pilot cluster randomized controlled trial assessing uptake of PrEP and contraception in hair salons in South Africa
by: Ingrid V. Bassett, et al.
Published: (2025-02-01)