A False Case of Clozapine-Resistant Schizophrenia
One of the subjects that most concerns physicians is treatment-resistance. About 30%–60% of schizophrenia patients do not respond adequately to antipsychotic treatment and are known as refractory schizophrenia patients. Clozapine has been the drug of choice in such cases. However, approximately 30%...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2010/534027 |
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| author | J. P. Maia-de-Oliveira J. P. Pinto V. Alexandre J. P. Machado-de-Sousa S. L. Morais C. Chaves A. C. Sakamoto A. W. Zuardi J. A. S. Crippa J. E. Hallak |
| author_facet | J. P. Maia-de-Oliveira J. P. Pinto V. Alexandre J. P. Machado-de-Sousa S. L. Morais C. Chaves A. C. Sakamoto A. W. Zuardi J. A. S. Crippa J. E. Hallak |
| author_sort | J. P. Maia-de-Oliveira |
| collection | DOAJ |
| description | One of the subjects that most concerns physicians is treatment-resistance. About 30%–60% of schizophrenia patients do not respond adequately to antipsychotic treatment and are known as refractory schizophrenia patients. Clozapine has been the drug of choice in such cases. However, approximately 30% of them do not respond to clozapine either. Here, we describe a patient with an initial diagnosis of refractory schizophrenia who had a history of dramatic aggressiveness. However, in this case, “refractoriness” was a wrong diagnosis. A case of psychosis secondary to epilepsy had been treated as schizophrenia for almost 20 years. Reports like this one are important because they remind us of how a thorough investigation can lead to the correct diagnosis and improve the patient's prognosis. |
| format | Article |
| id | doaj-art-0b5d9405b3124e58aad99dbec782d0de |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-0b5d9405b3124e58aad99dbec782d0de2025-02-03T01:02:02ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/534027534027A False Case of Clozapine-Resistant SchizophreniaJ. P. Maia-de-Oliveira0J. P. Pinto1V. Alexandre2J. P. Machado-de-Sousa3S. L. Morais4C. Chaves5A. C. Sakamoto6A. W. Zuardi7J. A. S. Crippa8J. E. Hallak9Department of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilDepartment of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilDepartment of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilDepartment of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilDepartment of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilDepartment of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilDepartment of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilDepartment of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilDepartment of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilDepartment of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School, University of São Paulo (USP), Hospital das Clinicas, TerceiroAndar, AvenidaBandeirantes Campus Universitario, 3900, Ribeirao Preto, SP 14049-900, BrazilOne of the subjects that most concerns physicians is treatment-resistance. About 30%–60% of schizophrenia patients do not respond adequately to antipsychotic treatment and are known as refractory schizophrenia patients. Clozapine has been the drug of choice in such cases. However, approximately 30% of them do not respond to clozapine either. Here, we describe a patient with an initial diagnosis of refractory schizophrenia who had a history of dramatic aggressiveness. However, in this case, “refractoriness” was a wrong diagnosis. A case of psychosis secondary to epilepsy had been treated as schizophrenia for almost 20 years. Reports like this one are important because they remind us of how a thorough investigation can lead to the correct diagnosis and improve the patient's prognosis.http://dx.doi.org/10.1155/2010/534027 |
| spellingShingle | J. P. Maia-de-Oliveira J. P. Pinto V. Alexandre J. P. Machado-de-Sousa S. L. Morais C. Chaves A. C. Sakamoto A. W. Zuardi J. A. S. Crippa J. E. Hallak A False Case of Clozapine-Resistant Schizophrenia Case Reports in Medicine |
| title | A False Case of Clozapine-Resistant Schizophrenia |
| title_full | A False Case of Clozapine-Resistant Schizophrenia |
| title_fullStr | A False Case of Clozapine-Resistant Schizophrenia |
| title_full_unstemmed | A False Case of Clozapine-Resistant Schizophrenia |
| title_short | A False Case of Clozapine-Resistant Schizophrenia |
| title_sort | false case of clozapine resistant schizophrenia |
| url | http://dx.doi.org/10.1155/2010/534027 |
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