Enterobius vermicularis as a cause of acute appendicitis in a child with acute lymphocytic leukemia: A case report

Background: Enterobius vermicularis is the most important intestinal parasite in children worldwide. When this parasite migrates unexpectedly, the larvae move out of the intestine and enter organs such as the appendix, and can cause health risks. Case presentation: An 8-year-old boy was admitted to...

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Main Authors: Shalaleh Ganji, Iraj Mobedi, Azim Rezamand, Farshid Ardabili, Pooya Yari, Majid Khanmohammadi
Format: Article
Language:English
Published: Golestan University of Medical Sciences 2025-01-01
Series:Medical Laboratory Journal
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Online Access:http://mlj.goums.ac.ir/article-1-1687-en.pdf
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author Shalaleh Ganji
Iraj Mobedi
Azim Rezamand
Farshid Ardabili
Pooya Yari
Majid Khanmohammadi
author_facet Shalaleh Ganji
Iraj Mobedi
Azim Rezamand
Farshid Ardabili
Pooya Yari
Majid Khanmohammadi
author_sort Shalaleh Ganji
collection DOAJ
description Background: Enterobius vermicularis is the most important intestinal parasite in children worldwide. When this parasite migrates unexpectedly, the larvae move out of the intestine and enter organs such as the appendix, and can cause health risks. Case presentation: An 8-year-old boy was admitted to the oncology clinic of Tabriz Children’s Hospital, complaining of fever of 39-40°C with abdominal pain, cramps, loss of appetite, weakness, and fatigue, associated with cervical lymphadenopathy, hepatomegaly, axillary mass, abdominal upper thigh, maculopapular rashes, and tiny petechiae on the chest and abdomen. Results: On CT examination of the chest, moderate mediastinal and mesenteric lymphadenopathy was noted. The patient was hospitalized with a definitive diagnosis of acute lymphoblastic leukemia. On the seventh day of hospitalization, the patient developed additive colic pain (Contraction and cramping) around the umbilicus and concomitantly developed pain downward and rightward into the abdomen. Based on the clinical findings, the patient was thought to have acute appendicitis. Pathological examinations showed that E. vermicularis was the cause of the appendicitis. Conclusion: The results of this study indicate that this parasite may be associated with inflammation of the appendix in patients with acute lymphoblastic leukemia. A screening program is still required in patients with immunodeficiency or those taking immunosuppressive drugs.
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spelling doaj-art-0b57df4eca0d495e933db6d3e7e22a4b2025-08-20T02:38:19ZengGolestan University of Medical SciencesMedical Laboratory Journal2538-44492025-01-011913235Enterobius vermicularis as a cause of acute appendicitis in a child with acute lymphocytic leukemia: A case reportShalaleh Ganji0Iraj Mobedi1Azim Rezamand2Farshid Ardabili3Pooya Yari4Majid Khanmohammadi5 Department of Pediatric, Children’s Hospital, Tabriz University of Medical Sciences, Tabriz, Iran Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical sciences, Tehran, Iran Department of Pediatric, Children’s Hospital, Tabriz University of Medical Sciences, Tabriz, Iran Department of Biology, Faculty of Sciences, University of Maragheh, Maragheh, Iran Department of Medical Biotechnology, School of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran Department of Laboratory Sciences, Mara.C., Islamic Azad University, Marand, Iran Background: Enterobius vermicularis is the most important intestinal parasite in children worldwide. When this parasite migrates unexpectedly, the larvae move out of the intestine and enter organs such as the appendix, and can cause health risks. Case presentation: An 8-year-old boy was admitted to the oncology clinic of Tabriz Children’s Hospital, complaining of fever of 39-40°C with abdominal pain, cramps, loss of appetite, weakness, and fatigue, associated with cervical lymphadenopathy, hepatomegaly, axillary mass, abdominal upper thigh, maculopapular rashes, and tiny petechiae on the chest and abdomen. Results: On CT examination of the chest, moderate mediastinal and mesenteric lymphadenopathy was noted. The patient was hospitalized with a definitive diagnosis of acute lymphoblastic leukemia. On the seventh day of hospitalization, the patient developed additive colic pain (Contraction and cramping) around the umbilicus and concomitantly developed pain downward and rightward into the abdomen. Based on the clinical findings, the patient was thought to have acute appendicitis. Pathological examinations showed that E. vermicularis was the cause of the appendicitis. Conclusion: The results of this study indicate that this parasite may be associated with inflammation of the appendix in patients with acute lymphoblastic leukemia. A screening program is still required in patients with immunodeficiency or those taking immunosuppressive drugs.http://mlj.goums.ac.ir/article-1-1687-en.pdfenterobiusappendicitisacute lymphocytic leukemia
spellingShingle Shalaleh Ganji
Iraj Mobedi
Azim Rezamand
Farshid Ardabili
Pooya Yari
Majid Khanmohammadi
Enterobius vermicularis as a cause of acute appendicitis in a child with acute lymphocytic leukemia: A case report
Medical Laboratory Journal
enterobius
appendicitis
acute lymphocytic leukemia
title Enterobius vermicularis as a cause of acute appendicitis in a child with acute lymphocytic leukemia: A case report
title_full Enterobius vermicularis as a cause of acute appendicitis in a child with acute lymphocytic leukemia: A case report
title_fullStr Enterobius vermicularis as a cause of acute appendicitis in a child with acute lymphocytic leukemia: A case report
title_full_unstemmed Enterobius vermicularis as a cause of acute appendicitis in a child with acute lymphocytic leukemia: A case report
title_short Enterobius vermicularis as a cause of acute appendicitis in a child with acute lymphocytic leukemia: A case report
title_sort enterobius vermicularis as a cause of acute appendicitis in a child with acute lymphocytic leukemia a case report
topic enterobius
appendicitis
acute lymphocytic leukemia
url http://mlj.goums.ac.ir/article-1-1687-en.pdf
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