Rifaximin resistance in Clostridioides difficile is associated with specific rpoB alleles and multilocus sequence typing (MLST) clades

Rifaximin resistance in Clostridioides difficile is associated with specific rpoB alleles and multilocus sequence typing (MLST) clades

Abstract Background and Objectives Rifaximin (RFX) has recently been suggested as an alternative treatment option for Clostridioides difficile infection. This study reports the survey on RFX susceptibility within a C. difficile test cohort that represents the five clinically relevant phylogenetic cl...

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Bibliographic Details
Main Authors: Julian Schwanbeck, Friederike Laukien, Thomas Riedel, Boyke Bunk, Philipp Halama, Cathrin Spröer, Jörg Overmann, Paul Cooper, R. Lia Kusumawati, Uwe Groß, Wolfgang Bohne, Andreas E. Zautner
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Microbiology
Subjects:
Clostridioides difficile
Nosocomial diarrhea
Antibiotic resistance
Rifaximin
Germany
Ghana
Online Access:https://doi.org/10.1186/s12866-025-04164-4
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