Secular trends in types of cardiovascular disease in the West of Scotland
Objective Historical reductions in cardiovascular disease (CVD) due to lifestyle and treatment improvements are now threatened by factors such as increasing obesity and diabetes, but the relative importance of different risk factors varies by CVD condition. This study describes secular trends in CVD...
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BMJ Publishing Group
2025-03-01
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| Series: | Open Heart |
| Online Access: | https://openheart.bmj.com/content/12/1/e003003.full |
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| author | Naveed Sattar Colin Berry Daniel F Mackay Christian Delles Ruth Dundas Frederick K Ho Sandosh Padmanabhan Claudia Geue Michael Fleming Denise Brown Clea du Toit Jill Pell Claire E Hastie Anna Kamdar Jocelyn M Friday Tran Q B Tran Alan Stevenson Jim D Lewsey |
| author_facet | Naveed Sattar Colin Berry Daniel F Mackay Christian Delles Ruth Dundas Frederick K Ho Sandosh Padmanabhan Claudia Geue Michael Fleming Denise Brown Clea du Toit Jill Pell Claire E Hastie Anna Kamdar Jocelyn M Friday Tran Q B Tran Alan Stevenson Jim D Lewsey |
| author_sort | Naveed Sattar |
| collection | DOAJ |
| description | Objective Historical reductions in cardiovascular disease (CVD) due to lifestyle and treatment improvements are now threatened by factors such as increasing obesity and diabetes, but the relative importance of different risk factors varies by CVD condition. This study describes secular trends in CVD events by individual condition from 2012 to 2022.Methods In a cohort of 452 094 Greater Glasgow and Clyde residents aged ≥51 years, linked hospital admission and death data were used to ascertain total annual events for ischaemic heart disease (IHD), myocardial infarction (MI), heart failure (HF), atrial fibrillation (AF), stroke, abdominal aortic aneurysm (AAA) and peripheral artery disease (PAD). Poisson regressions with robust standard errors were used to examine the relative change in event rates over time, overall and by subgroup.Results Overall, the event rate ratios (RRs) for IHD, MI, AF and AAA all fell between 2012 and 2021 after adjustment for age, sex and deprivation. However, on subgroup analysis, the RRs increased between 2012 and 2022 among those aged 51–64 years for HF (RR 1.5), stroke (RR 1.4) and PAD (RR 1.8).Conclusions Overall declines in most types of CVD mask an increasing burden of events relating to HF, stroke and PAD among individuals aged 51–64 years. |
| format | Article |
| id | doaj-art-0b4a894df8944f27b7dcd32c40e8e58d |
| institution | DOAJ |
| issn | 2053-3624 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | Open Heart |
| spelling | doaj-art-0b4a894df8944f27b7dcd32c40e8e58d2025-08-20T02:40:39ZengBMJ Publishing GroupOpen Heart2053-36242025-03-0112110.1136/openhrt-2024-003003Secular trends in types of cardiovascular disease in the West of ScotlandNaveed Sattar0Colin Berry1Daniel F Mackay2Christian Delles3Ruth Dundas4Frederick K Ho5Sandosh Padmanabhan6Claudia Geue7Michael Fleming8Denise Brown9Clea du Toit10Jill Pell11Claire E Hastie12Anna Kamdar13Jocelyn M Friday14Tran Q B Tran15Alan Stevenson16Jim D Lewsey17School of Cardiovascular & Metabolic Health, University of Glasgow, Glasgow, UKCardiology, Golden Jubilee National Hospital, Clydebank, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKSchool of Cardiovascular & Metabolic Health, University of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKSchool of Cardiovascular & Metabolic Health, University of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKDigital Health Validation Lab, University of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKCardiology, Golden Jubilee National Hospital, Clydebank, UKSchool of Cardiovascular & Metabolic Health, University of Glasgow, Glasgow, UKSchool of Cardiovascular & Metabolic Health, University of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKSchool of Health & Wellbeing, University of Glasgow, Glasgow, UKObjective Historical reductions in cardiovascular disease (CVD) due to lifestyle and treatment improvements are now threatened by factors such as increasing obesity and diabetes, but the relative importance of different risk factors varies by CVD condition. This study describes secular trends in CVD events by individual condition from 2012 to 2022.Methods In a cohort of 452 094 Greater Glasgow and Clyde residents aged ≥51 years, linked hospital admission and death data were used to ascertain total annual events for ischaemic heart disease (IHD), myocardial infarction (MI), heart failure (HF), atrial fibrillation (AF), stroke, abdominal aortic aneurysm (AAA) and peripheral artery disease (PAD). Poisson regressions with robust standard errors were used to examine the relative change in event rates over time, overall and by subgroup.Results Overall, the event rate ratios (RRs) for IHD, MI, AF and AAA all fell between 2012 and 2021 after adjustment for age, sex and deprivation. However, on subgroup analysis, the RRs increased between 2012 and 2022 among those aged 51–64 years for HF (RR 1.5), stroke (RR 1.4) and PAD (RR 1.8).Conclusions Overall declines in most types of CVD mask an increasing burden of events relating to HF, stroke and PAD among individuals aged 51–64 years.https://openheart.bmj.com/content/12/1/e003003.full |
| spellingShingle | Naveed Sattar Colin Berry Daniel F Mackay Christian Delles Ruth Dundas Frederick K Ho Sandosh Padmanabhan Claudia Geue Michael Fleming Denise Brown Clea du Toit Jill Pell Claire E Hastie Anna Kamdar Jocelyn M Friday Tran Q B Tran Alan Stevenson Jim D Lewsey Secular trends in types of cardiovascular disease in the West of Scotland Open Heart |
| title | Secular trends in types of cardiovascular disease in the West of Scotland |
| title_full | Secular trends in types of cardiovascular disease in the West of Scotland |
| title_fullStr | Secular trends in types of cardiovascular disease in the West of Scotland |
| title_full_unstemmed | Secular trends in types of cardiovascular disease in the West of Scotland |
| title_short | Secular trends in types of cardiovascular disease in the West of Scotland |
| title_sort | secular trends in types of cardiovascular disease in the west of scotland |
| url | https://openheart.bmj.com/content/12/1/e003003.full |
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