Genetic and Iatrogenic Defects in Peripheral Tolerance Associated with Anti-Nephrin Antibody-Associated Minimal Change Disease

Genetic and Iatrogenic Defects in Peripheral Tolerance Associated with Anti-Nephrin Antibody-Associated Minimal Change Disease

Introduction: Minimal change disease (MCD) is a common cause of nephrotic syndrome in children and adults. Immune dysregulation is a contributor, but the relative roles of individual components of the immune system in MCD pathogenesis remain unclear. Case Presentation: Here, we present 2...

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Main Authors: J. Ashley Jefferson, Karin Chen, Sangeeta Hingorani, A. Bilal Malik, Scott S. Tykodi, Keith H. Keller, Yuan Huang, Kelly D. Smith, Robyn C. Reed, Astrid Weins, Shreeram Akilesh
Format: Article
Language:English
Published: Karger Publishers 2025-01-01
Series:Glomerular Diseases
Online Access:https://karger.com/article/doi/10.1159/000543334
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