Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group
Glioneuronal neoplasms are rare tumors. Recently, an unusual glioneuronal tumor histologically showing neuropil-like islands has been described. Here, we present such a tumor originating from spinal cord of a 14-year-old girl, who has scoliosis and urinary incontinence. Microscopically, the glial co...
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Wiley
2014-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2014/471645 |
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| author | Nil Comunoglu Ozgur Kilickesmez Buge Oz |
| author_facet | Nil Comunoglu Ozgur Kilickesmez Buge Oz |
| author_sort | Nil Comunoglu |
| collection | DOAJ |
| description | Glioneuronal neoplasms are rare tumors. Recently, an unusual glioneuronal tumor histologically showing neuropil-like islands has been described. Here, we present such a tumor originating from spinal cord of a 14-year-old girl, who has scoliosis and urinary incontinence. Microscopically, the glial component was chiefly fibrillary astrocytic, punctuated by neuropil-like islands. Immunohistochemically, glial tissue was GFAP positive, and neuropil-like areas and big neurons were synaptophysin reactive. For astrocytic component Ki-67 proliferation index was 1% and p53 was immunonegative. This case is unique in that in the literature it is the second reported case in pediatric age group that is located at spinal cord. |
| format | Article |
| id | doaj-art-0b3bd0cbae9c4ee68e97e6a182e961f2 |
| institution | OA Journals |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-0b3bd0cbae9c4ee68e97e6a182e961f22025-08-20T02:03:43ZengWileyCase Reports in Pathology2090-67812090-679X2014-01-01201410.1155/2014/471645471645Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age GroupNil Comunoglu0Ozgur Kilickesmez1Buge Oz2Department of Pathology, Cerrahpasa Faculty of Medicine, Istanbul University, 34000 Istanbul, TurkeyDepartment of Radiology, Faculty of Medicine, Yeditepe University, Istanbul, TurkeyDepartment of Pathology, Cerrahpasa Faculty of Medicine, Istanbul University, 34000 Istanbul, TurkeyGlioneuronal neoplasms are rare tumors. Recently, an unusual glioneuronal tumor histologically showing neuropil-like islands has been described. Here, we present such a tumor originating from spinal cord of a 14-year-old girl, who has scoliosis and urinary incontinence. Microscopically, the glial component was chiefly fibrillary astrocytic, punctuated by neuropil-like islands. Immunohistochemically, glial tissue was GFAP positive, and neuropil-like areas and big neurons were synaptophysin reactive. For astrocytic component Ki-67 proliferation index was 1% and p53 was immunonegative. This case is unique in that in the literature it is the second reported case in pediatric age group that is located at spinal cord.http://dx.doi.org/10.1155/2014/471645 |
| spellingShingle | Nil Comunoglu Ozgur Kilickesmez Buge Oz Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group Case Reports in Pathology |
| title | Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group |
| title_full | Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group |
| title_fullStr | Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group |
| title_full_unstemmed | Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group |
| title_short | Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group |
| title_sort | spinal cord glioneuronal tumor with rosetted neuropil like islands in pediatric age group |
| url | http://dx.doi.org/10.1155/2014/471645 |
| work_keys_str_mv | AT nilcomunoglu spinalcordglioneuronaltumorwithrosettedneuropillikeislandsinpediatricagegroup AT ozgurkilickesmez spinalcordglioneuronaltumorwithrosettedneuropillikeislandsinpediatricagegroup AT bugeoz spinalcordglioneuronaltumorwithrosettedneuropillikeislandsinpediatricagegroup |