Determinants of Selected Cardiovascular Diseases among Adult Patients at Cardiac Clinic of Debre Berhan Referral Hospital, Ethiopia: Unmatched Case-Control Study

Background. Africans are experiencing a rapid epidemiological transition characterized by urbanization and lifestyle changes, which are thought to contribute to increased incidence and prevalence of cardiovascular diseases (CVDs) in many African countries, including Ethiopia. Despite this, however,...

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Main Authors: Shenkut Aragaw, Esubalew Tesfahun, Behailu Tariku Derseh, Betegiorgis Mamo
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/2020/7036151
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author Shenkut Aragaw
Esubalew Tesfahun
Behailu Tariku Derseh
Betegiorgis Mamo
author_facet Shenkut Aragaw
Esubalew Tesfahun
Behailu Tariku Derseh
Betegiorgis Mamo
author_sort Shenkut Aragaw
collection DOAJ
description Background. Africans are experiencing a rapid epidemiological transition characterized by urbanization and lifestyle changes, which are thought to contribute to increased incidence and prevalence of cardiovascular diseases (CVDs) in many African countries, including Ethiopia. Despite this, however, there is scarcity of evidence on cardiovascular disease risk factors among adults in the current research setting. This study thus aimed at assessing determinants of selected cardiovascular diseases among adult patients at Debre Berhan Referral Hospital (DBRH). Methodology. An unmatched case-control study was conducted on 143 newly diagnosed patients with CVDs and 286 controls at the cardiac clinic of DBRH from June to September 2017. Primary data were collected using the WHO-STEPS wise structured questionnaires. Multiple logistic regression analysis was used to identify potential risk factors for cardiovascular diseases at p values < 0.05. Result. The mean age of study participants is estimated as 45.5±13.8 and ranges from 25 to 64 years. Sixty-one (42.7%) of cases and 147 (51.4%) of controls are males. Half of the cases (49.9%) had ischemic heart diseases (IHD), and 44.1% of cases had hypertensive heart disease (HHD), whereas the rest had chronic valvular heart disease (CRVHD) (4.2%) and peripheral and vascular disease (2.1%). This study identified older age as a risk factor for CVD: age group 35–44 years (adjusted odds ratio AOR=2.20; 95% CI: 1.05–4.62), 45-54 years (AOR=4.23; 95% CI: 2.19–8.16), and 55-64 years (AOR=5.98; 95% CI: 3.26–10.98). Other risk factors were smoking history (AOR=9.52; 95% CI: 2.12–42.8), low level of physical activity (AOR=2.19; 95% CI: 1.10–5.02), and higher waist circumference (AOR=2.75; 95% CI: 1.16–6.56). Conclusion. This study has demonstrated that the most frequent risk factors for CVD were older age, cigarette smoking, physical inactivity, and abdominal obesity. Therefore, behavior change communication focusing on lifestyle modification including regular physical activities, smoking cessation, and a balanced diet should be strengthened.
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spelling doaj-art-0b2ea279e0d64bd2bfabac6cf0af41152025-08-20T02:03:08ZengWileyCardiovascular Therapeutics1755-59141755-59222020-01-01202010.1155/2020/70361517036151Determinants of Selected Cardiovascular Diseases among Adult Patients at Cardiac Clinic of Debre Berhan Referral Hospital, Ethiopia: Unmatched Case-Control StudyShenkut Aragaw0Esubalew Tesfahun1Behailu Tariku Derseh2Betegiorgis Mamo3Public Health Department, College of Health Sciences, Debre Berhan University, Debre Berhan, EthiopiaPublic Health Department, College of Health Sciences, Debre Berhan University, Debre Berhan, EthiopiaPublic Health Department, College of Health Sciences, Debre Berhan University, Debre Berhan, EthiopiaDepartment of English, College of Social Sciences, Debre Berhan University, Debre Berhan, EthiopiaBackground. Africans are experiencing a rapid epidemiological transition characterized by urbanization and lifestyle changes, which are thought to contribute to increased incidence and prevalence of cardiovascular diseases (CVDs) in many African countries, including Ethiopia. Despite this, however, there is scarcity of evidence on cardiovascular disease risk factors among adults in the current research setting. This study thus aimed at assessing determinants of selected cardiovascular diseases among adult patients at Debre Berhan Referral Hospital (DBRH). Methodology. An unmatched case-control study was conducted on 143 newly diagnosed patients with CVDs and 286 controls at the cardiac clinic of DBRH from June to September 2017. Primary data were collected using the WHO-STEPS wise structured questionnaires. Multiple logistic regression analysis was used to identify potential risk factors for cardiovascular diseases at p values < 0.05. Result. The mean age of study participants is estimated as 45.5±13.8 and ranges from 25 to 64 years. Sixty-one (42.7%) of cases and 147 (51.4%) of controls are males. Half of the cases (49.9%) had ischemic heart diseases (IHD), and 44.1% of cases had hypertensive heart disease (HHD), whereas the rest had chronic valvular heart disease (CRVHD) (4.2%) and peripheral and vascular disease (2.1%). This study identified older age as a risk factor for CVD: age group 35–44 years (adjusted odds ratio AOR=2.20; 95% CI: 1.05–4.62), 45-54 years (AOR=4.23; 95% CI: 2.19–8.16), and 55-64 years (AOR=5.98; 95% CI: 3.26–10.98). Other risk factors were smoking history (AOR=9.52; 95% CI: 2.12–42.8), low level of physical activity (AOR=2.19; 95% CI: 1.10–5.02), and higher waist circumference (AOR=2.75; 95% CI: 1.16–6.56). Conclusion. This study has demonstrated that the most frequent risk factors for CVD were older age, cigarette smoking, physical inactivity, and abdominal obesity. Therefore, behavior change communication focusing on lifestyle modification including regular physical activities, smoking cessation, and a balanced diet should be strengthened.http://dx.doi.org/10.1155/2020/7036151
spellingShingle Shenkut Aragaw
Esubalew Tesfahun
Behailu Tariku Derseh
Betegiorgis Mamo
Determinants of Selected Cardiovascular Diseases among Adult Patients at Cardiac Clinic of Debre Berhan Referral Hospital, Ethiopia: Unmatched Case-Control Study
Cardiovascular Therapeutics
title Determinants of Selected Cardiovascular Diseases among Adult Patients at Cardiac Clinic of Debre Berhan Referral Hospital, Ethiopia: Unmatched Case-Control Study
title_full Determinants of Selected Cardiovascular Diseases among Adult Patients at Cardiac Clinic of Debre Berhan Referral Hospital, Ethiopia: Unmatched Case-Control Study
title_fullStr Determinants of Selected Cardiovascular Diseases among Adult Patients at Cardiac Clinic of Debre Berhan Referral Hospital, Ethiopia: Unmatched Case-Control Study
title_full_unstemmed Determinants of Selected Cardiovascular Diseases among Adult Patients at Cardiac Clinic of Debre Berhan Referral Hospital, Ethiopia: Unmatched Case-Control Study
title_short Determinants of Selected Cardiovascular Diseases among Adult Patients at Cardiac Clinic of Debre Berhan Referral Hospital, Ethiopia: Unmatched Case-Control Study
title_sort determinants of selected cardiovascular diseases among adult patients at cardiac clinic of debre berhan referral hospital ethiopia unmatched case control study
url http://dx.doi.org/10.1155/2020/7036151
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