Cortical spreading depression in migraine-time to reconsider?
New evidence concerning the pathophysiology of migraine has come from the results of therapeutic transcranial magnetic stimulation (tTMS). The instantaneous responses to single pulses applied during the aura or headache phase, together with a number of other observations, make it unlikely that corti...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
2015-08-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000800714&lng=en&tlng=en |
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| _version_ | 1849308452874092544 |
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| author | Alan J McComas Adrian R M Upton |
| author_facet | Alan J McComas Adrian R M Upton |
| author_sort | Alan J McComas |
| collection | DOAJ |
| description | New evidence concerning the pathophysiology of migraine has come from the results of therapeutic transcranial magnetic stimulation (tTMS). The instantaneous responses to single pulses applied during the aura or headache phase, together with a number of other observations, make it unlikely that cortical spreading depression is involved in migraine. tTMS is considered to act by abolishing abnormal impulse activity in cortical pyramidal neurons and a suggestion is made as to how this activity could arise. |
| format | Article |
| id | doaj-art-0b28803b5caa4ff6b2e7648b87935f3e |
| institution | Kabale University |
| issn | 1678-4227 |
| language | English |
| publishDate | 2015-08-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-0b28803b5caa4ff6b2e7648b87935f3e2025-08-20T03:54:28ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272015-08-0173871472110.1590/0004-282X20150094S0004-282X2015000800714Cortical spreading depression in migraine-time to reconsider?Alan J McComasAdrian R M UptonNew evidence concerning the pathophysiology of migraine has come from the results of therapeutic transcranial magnetic stimulation (tTMS). The instantaneous responses to single pulses applied during the aura or headache phase, together with a number of other observations, make it unlikely that cortical spreading depression is involved in migraine. tTMS is considered to act by abolishing abnormal impulse activity in cortical pyramidal neurons and a suggestion is made as to how this activity could arise.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000800714&lng=en&tlng=enenxaquecadepressão alastranteestimulação magnética transcraniana |
| spellingShingle | Alan J McComas Adrian R M Upton Cortical spreading depression in migraine-time to reconsider? Arquivos de Neuro-Psiquiatria enxaqueca depressão alastrante estimulação magnética transcraniana |
| title | Cortical spreading depression in migraine-time to reconsider? |
| title_full | Cortical spreading depression in migraine-time to reconsider? |
| title_fullStr | Cortical spreading depression in migraine-time to reconsider? |
| title_full_unstemmed | Cortical spreading depression in migraine-time to reconsider? |
| title_short | Cortical spreading depression in migraine-time to reconsider? |
| title_sort | cortical spreading depression in migraine time to reconsider |
| topic | enxaqueca depressão alastrante estimulação magnética transcraniana |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000800714&lng=en&tlng=en |
| work_keys_str_mv | AT alanjmccomas corticalspreadingdepressioninmigrainetimetoreconsider AT adrianrmupton corticalspreadingdepressioninmigrainetimetoreconsider |