Persistent symptoms in euthyroid Hashimoto’s thyroiditis: current hypotheses and emerging management strategies

Persistent symptoms in euthyroid Hashimoto’s thyroiditis: current hypotheses and emerging management strategies

A substantial proportion of patients with Hashimoto’s thyroiditis (HT) continue to experience persistent symptoms despite achieving biochemical euthyroidism, either with or without levothyroxine (LT4) replacement therapy. Several pathophysiological mechanisms have been proposed to explain this clini...

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Bibliographic Details
Main Authors: Hui Zhang, Wenting Tong, Weiyong Zeng, Hongyan Luo, Licai Zhang, Jiasheng Feng, Yang Xiao, Gankun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Endocrinology
Subjects:
Hashimoto’s thyreoiditis
biochemical euthroidism
therapy
autoimmunity modulation
symptoms
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1627787/full
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