Minimally Invasive Surgical Techniques for Renal Cell Carcinoma with Intravenous Tumor Thrombus: A Systematic Review of Laparoscopic and Robotic-Assisted Approaches
Introduction: Locally advanced renal cell carcinoma (RCC) with intravenous tumor thrombus (IVTT) represents 4–10% of renal tumors. This review assesses the safety and outcomes of minimally invasive techniques, specifically laparoscopic (LAP) and robotic-assisted (RA) methods, for treating RCC with I...
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MDPI AG
2025-04-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/32/5/256 |
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| author | Yiting Wu Shuyang Feng Ping Fu |
| author_facet | Yiting Wu Shuyang Feng Ping Fu |
| author_sort | Yiting Wu |
| collection | DOAJ |
| description | Introduction: Locally advanced renal cell carcinoma (RCC) with intravenous tumor thrombus (IVTT) represents 4–10% of renal tumors. This review assesses the safety and outcomes of minimally invasive techniques, specifically laparoscopic (LAP) and robotic-assisted (RA) methods, for treating RCC with IVTT. Methods: A literature search across several databases identified 54 studies (42 case series, 12 cohort studies) for analysis. Perioperative outcomes, including operative time, blood loss, transfusion rates, length of stay, and complications, were compared based on IVTT levels. Results: LAP and RA techniques were feasible for low-level IVTT, showing similar perioperative results. RA outperformed LAP in high-level IVTT with shorter operative times and lower blood loss and transfusion rates, despite managing more complex cases. RA maintained stable cancer-specific mortality (CSM) and metastasis rates, whereas LAP exhibited higher rates in high-level cases. Both techniques had low local recurrence rates. Conclusion: RA may be a superior option for RCC with IVTT, especially in high-level cases, but the data come mainly from specialized centers, signaling a need for multicenter validation and standardized criteria. Long-term outcomes require further study to assess RA’s non-inferiority to LAP. |
| format | Article |
| id | doaj-art-0b1f4d25bd2e4d7a8c1183952ca7cc02 |
| institution | OA Journals |
| issn | 1198-0052 1718-7729 |
| language | English |
| publishDate | 2025-04-01 |
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| series | Current Oncology |
| spelling | doaj-art-0b1f4d25bd2e4d7a8c1183952ca7cc022025-08-20T02:33:31ZengMDPI AGCurrent Oncology1198-00521718-77292025-04-0132525610.3390/curroncol32050256Minimally Invasive Surgical Techniques for Renal Cell Carcinoma with Intravenous Tumor Thrombus: A Systematic Review of Laparoscopic and Robotic-Assisted ApproachesYiting Wu0Shuyang Feng1Ping Fu2Department of Nephrology, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Urology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Nephrology, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu 610041, ChinaIntroduction: Locally advanced renal cell carcinoma (RCC) with intravenous tumor thrombus (IVTT) represents 4–10% of renal tumors. This review assesses the safety and outcomes of minimally invasive techniques, specifically laparoscopic (LAP) and robotic-assisted (RA) methods, for treating RCC with IVTT. Methods: A literature search across several databases identified 54 studies (42 case series, 12 cohort studies) for analysis. Perioperative outcomes, including operative time, blood loss, transfusion rates, length of stay, and complications, were compared based on IVTT levels. Results: LAP and RA techniques were feasible for low-level IVTT, showing similar perioperative results. RA outperformed LAP in high-level IVTT with shorter operative times and lower blood loss and transfusion rates, despite managing more complex cases. RA maintained stable cancer-specific mortality (CSM) and metastasis rates, whereas LAP exhibited higher rates in high-level cases. Both techniques had low local recurrence rates. Conclusion: RA may be a superior option for RCC with IVTT, especially in high-level cases, but the data come mainly from specialized centers, signaling a need for multicenter validation and standardized criteria. Long-term outcomes require further study to assess RA’s non-inferiority to LAP.https://www.mdpi.com/1718-7729/32/5/256renal cell carcinoma (RCC)intravenous tumor thrombus (IVTT)minimally invasive surgerylaparoscopic surgeryrobotic-assisted surgeryoncological safety |
| spellingShingle | Yiting Wu Shuyang Feng Ping Fu Minimally Invasive Surgical Techniques for Renal Cell Carcinoma with Intravenous Tumor Thrombus: A Systematic Review of Laparoscopic and Robotic-Assisted Approaches Current Oncology renal cell carcinoma (RCC) intravenous tumor thrombus (IVTT) minimally invasive surgery laparoscopic surgery robotic-assisted surgery oncological safety |
| title | Minimally Invasive Surgical Techniques for Renal Cell Carcinoma with Intravenous Tumor Thrombus: A Systematic Review of Laparoscopic and Robotic-Assisted Approaches |
| title_full | Minimally Invasive Surgical Techniques for Renal Cell Carcinoma with Intravenous Tumor Thrombus: A Systematic Review of Laparoscopic and Robotic-Assisted Approaches |
| title_fullStr | Minimally Invasive Surgical Techniques for Renal Cell Carcinoma with Intravenous Tumor Thrombus: A Systematic Review of Laparoscopic and Robotic-Assisted Approaches |
| title_full_unstemmed | Minimally Invasive Surgical Techniques for Renal Cell Carcinoma with Intravenous Tumor Thrombus: A Systematic Review of Laparoscopic and Robotic-Assisted Approaches |
| title_short | Minimally Invasive Surgical Techniques for Renal Cell Carcinoma with Intravenous Tumor Thrombus: A Systematic Review of Laparoscopic and Robotic-Assisted Approaches |
| title_sort | minimally invasive surgical techniques for renal cell carcinoma with intravenous tumor thrombus a systematic review of laparoscopic and robotic assisted approaches |
| topic | renal cell carcinoma (RCC) intravenous tumor thrombus (IVTT) minimally invasive surgery laparoscopic surgery robotic-assisted surgery oncological safety |
| url | https://www.mdpi.com/1718-7729/32/5/256 |
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