Wall-eyed bilateral internuclear ophthalmoplegia (webino syndrome) and myelopathy in pyoderma gangrenosum

A 35-year-old female with pyoderma gangrenosum developed paraparesis with a sensory level at L1. Three months later she complained of diplopia and was found to have bilateral internuclear ophthalmoplegia with exotropia and no ocular convergence. The term Webino syndrome has been coined to design thi...

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Main Authors: Marco Aurélio Lana, Paulo Roberto R. Moreira, Leonardo B. Neves
Format: Article
Language:English
Published: Thieme Revinter Publicações 1990-12-01
Series:Arquivos de Neuro-Psiquiatria
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1990000400016&lng=en&tlng=en
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author Marco Aurélio Lana
Paulo Roberto R. Moreira
Leonardo B. Neves
author_facet Marco Aurélio Lana
Paulo Roberto R. Moreira
Leonardo B. Neves
author_sort Marco Aurélio Lana
collection DOAJ
description A 35-year-old female with pyoderma gangrenosum developed paraparesis with a sensory level at L1. Three months later she complained of diplopia and was found to have bilateral internuclear ophthalmoplegia with exotropia and no ocular convergence. The term Webino syndrome has been coined to design this set of neuro-opthalmologic findings. Although it was initially attributed to lesions affecting the medial longitudinal fasciculus and the medial rectus subnuclei of the oculomotor complex in the midbrain the exact location of the lesion is still disputed. In the present case both myelopathy and Webino syndrome were probably due to vascular occlusive disease resulting from central nervous system vasculitis occurring in concomitance to pyoderma gangrenosum.
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publisher Thieme Revinter Publicações
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series Arquivos de Neuro-Psiquiatria
spelling doaj-art-0b1e6baf50dc4d0daa8876db05d614cf2025-08-20T01:59:30ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271990-12-0148449750110.1590/S0004-282X1990000400016S0004-282X1990000400016Wall-eyed bilateral internuclear ophthalmoplegia (webino syndrome) and myelopathy in pyoderma gangrenosumMarco Aurélio Lana0Paulo Roberto R. Moreira1Leonardo B. Neves2Universidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisA 35-year-old female with pyoderma gangrenosum developed paraparesis with a sensory level at L1. Three months later she complained of diplopia and was found to have bilateral internuclear ophthalmoplegia with exotropia and no ocular convergence. The term Webino syndrome has been coined to design this set of neuro-opthalmologic findings. Although it was initially attributed to lesions affecting the medial longitudinal fasciculus and the medial rectus subnuclei of the oculomotor complex in the midbrain the exact location of the lesion is still disputed. In the present case both myelopathy and Webino syndrome were probably due to vascular occlusive disease resulting from central nervous system vasculitis occurring in concomitance to pyoderma gangrenosum.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1990000400016&lng=en&tlng=en
spellingShingle Marco Aurélio Lana
Paulo Roberto R. Moreira
Leonardo B. Neves
Wall-eyed bilateral internuclear ophthalmoplegia (webino syndrome) and myelopathy in pyoderma gangrenosum
Arquivos de Neuro-Psiquiatria
title Wall-eyed bilateral internuclear ophthalmoplegia (webino syndrome) and myelopathy in pyoderma gangrenosum
title_full Wall-eyed bilateral internuclear ophthalmoplegia (webino syndrome) and myelopathy in pyoderma gangrenosum
title_fullStr Wall-eyed bilateral internuclear ophthalmoplegia (webino syndrome) and myelopathy in pyoderma gangrenosum
title_full_unstemmed Wall-eyed bilateral internuclear ophthalmoplegia (webino syndrome) and myelopathy in pyoderma gangrenosum
title_short Wall-eyed bilateral internuclear ophthalmoplegia (webino syndrome) and myelopathy in pyoderma gangrenosum
title_sort wall eyed bilateral internuclear ophthalmoplegia webino syndrome and myelopathy in pyoderma gangrenosum
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1990000400016&lng=en&tlng=en
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