Predictors of depression among Chinese college students: a machine learning approach

Abstract Background Depression is highly prevalent among college students, posing a significant public health challenge. Identifying key predictors of depression is essential for developing effective interventions. This study aimed to analyze potential depression risk factors among Chinese college s...

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Main Authors: Lin Luo, Junfeng Yuan, Chenghan Wu, Yanling Wang, Rui Zhu, Huilin Xu, Luqin Zhang, Zhongge Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-025-21632-8
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author Lin Luo
Junfeng Yuan
Chenghan Wu
Yanling Wang
Rui Zhu
Huilin Xu
Luqin Zhang
Zhongge Zhang
author_facet Lin Luo
Junfeng Yuan
Chenghan Wu
Yanling Wang
Rui Zhu
Huilin Xu
Luqin Zhang
Zhongge Zhang
author_sort Lin Luo
collection DOAJ
description Abstract Background Depression is highly prevalent among college students, posing a significant public health challenge. Identifying key predictors of depression is essential for developing effective interventions. This study aimed to analyze potential depression risk factors among Chinese college students using the Random Forest Algorithm (RFA) and to explore gender differences in risk patterns. Methods A cross-sectional study was conducted with 10,043 undergraduate students from Guizhou Normal University. Thirty-three variables were analyzed using RFA. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D), with a score of ≥ 16 indicating depression risk. The variables included sociodemographic characteristics, physical and psychological health indicators, behavioral and lifestyle factors, socioeconomic conditions, and family mental health history. Results The RFA identified several factors associated with depression risk, with suicidal ideation, anxiety, and sleep quality exhibiting the strongest associations. Other significant predictors included academic stress, BMI, vital capacity, psychological resilience, physical fitness test scores, major satisfaction, and social network use. The model achieved an accuracy of 87.5% and an AUC of 0.927. Gender-stratified analysis suggested different patterns: physical fitness indicators showed stronger associations with depression risk among male students, while BMI was more strongly associated with depression risk among female students. Conclusions This cross-sectional study identified factors associated with depression risk among Chinese college students, with psychological factors showing the strongest associations. Gender-specific patterns were observed, suggesting the importance of considering gender differences when developing mental health interventions. However, longitudinal studies are required to establish causal relationships and validate these findings through intervention trials.
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spelling doaj-art-0b0dca4114ee4734ae91a7754cf43a4e2025-02-09T12:58:22ZengBMCBMC Public Health1471-24582025-02-0125111110.1186/s12889-025-21632-8Predictors of depression among Chinese college students: a machine learning approachLin Luo0Junfeng Yuan1Chenghan Wu2Yanling Wang3Rui Zhu4Huilin Xu5Luqin Zhang6Zhongge Zhang7School of Physical Education, Guizhou Normal UniversitySchool of Physical Education, Guizhou Normal UniversityGuizhou Center for Disease Control and PreventionSchool of Physical Education, Guizhou Normal UniversitySchool of Physical Education, Guizhou Normal UniversitySchool of Physical Education, Guizhou Normal UniversitySchool of Physical Education, Guizhou Normal UniversitySchool of Physical Education, Guizhou Normal UniversityAbstract Background Depression is highly prevalent among college students, posing a significant public health challenge. Identifying key predictors of depression is essential for developing effective interventions. This study aimed to analyze potential depression risk factors among Chinese college students using the Random Forest Algorithm (RFA) and to explore gender differences in risk patterns. Methods A cross-sectional study was conducted with 10,043 undergraduate students from Guizhou Normal University. Thirty-three variables were analyzed using RFA. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D), with a score of ≥ 16 indicating depression risk. The variables included sociodemographic characteristics, physical and psychological health indicators, behavioral and lifestyle factors, socioeconomic conditions, and family mental health history. Results The RFA identified several factors associated with depression risk, with suicidal ideation, anxiety, and sleep quality exhibiting the strongest associations. Other significant predictors included academic stress, BMI, vital capacity, psychological resilience, physical fitness test scores, major satisfaction, and social network use. The model achieved an accuracy of 87.5% and an AUC of 0.927. Gender-stratified analysis suggested different patterns: physical fitness indicators showed stronger associations with depression risk among male students, while BMI was more strongly associated with depression risk among female students. Conclusions This cross-sectional study identified factors associated with depression risk among Chinese college students, with psychological factors showing the strongest associations. Gender-specific patterns were observed, suggesting the importance of considering gender differences when developing mental health interventions. However, longitudinal studies are required to establish causal relationships and validate these findings through intervention trials.https://doi.org/10.1186/s12889-025-21632-8College student depressionMachine learningPredictorsGender differencesRandom forest algorithm
spellingShingle Lin Luo
Junfeng Yuan
Chenghan Wu
Yanling Wang
Rui Zhu
Huilin Xu
Luqin Zhang
Zhongge Zhang
Predictors of depression among Chinese college students: a machine learning approach
BMC Public Health
College student depression
Machine learning
Predictors
Gender differences
Random forest algorithm
title Predictors of depression among Chinese college students: a machine learning approach
title_full Predictors of depression among Chinese college students: a machine learning approach
title_fullStr Predictors of depression among Chinese college students: a machine learning approach
title_full_unstemmed Predictors of depression among Chinese college students: a machine learning approach
title_short Predictors of depression among Chinese college students: a machine learning approach
title_sort predictors of depression among chinese college students a machine learning approach
topic College student depression
Machine learning
Predictors
Gender differences
Random forest algorithm
url https://doi.org/10.1186/s12889-025-21632-8
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