Design of a novel filter paper based construct for rapid analysis of acetone.
The present work was focused to design a cheap, rapid, portable and easy to use filter paper based assay for the qualitative and quantitate analysis of acetone. Sodium alginate gel was loaded with the acetone specific optical signal probe, and subsequently coated onto filter paper surface to design...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199978&type=printable |
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| author | Sajid Rauf Yaqeen Ali Sabir Hussain Fakhar Ullah Akhtar Hayat |
| author_facet | Sajid Rauf Yaqeen Ali Sabir Hussain Fakhar Ullah Akhtar Hayat |
| author_sort | Sajid Rauf |
| collection | DOAJ |
| description | The present work was focused to design a cheap, rapid, portable and easy to use filter paper based assay for the qualitative and quantitate analysis of acetone. Sodium alginate gel was loaded with the acetone specific optical signal probe, and subsequently coated onto filter paper surface to design portable colorimetric assays for acetone monitoring. The color of the paper sensor strip was observed to change from dark yellow to light yellowish in the presence of varying concentrations of acetone. Three different color analyzing models including RGB, HSV, and LAB were employed to probe the output optical signal, and their performance was compared in terms of better interpretation of the generated signal. The LAB model was found to provide better analytical figures of merit with a linear response for the acetone concentration ranging from 2.5 to 1500 ppm, and a limit of detection of 0.5 ppm. Furthermore, the specificity of the designed filter paper based sensor was demonstrated against different common interfering compounds. The results demonstrated the potential of our proposed filter paper based sensor as a novel tool for the analysis of acetone. |
| format | Article |
| id | doaj-art-0aeb5576a89545fb93ef1265d26f940e |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-0aeb5576a89545fb93ef1265d26f940e2025-08-20T02:03:58ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01137e019997810.1371/journal.pone.0199978Design of a novel filter paper based construct for rapid analysis of acetone.Sajid RaufYaqeen AliSabir HussainFakhar UllahAkhtar HayatThe present work was focused to design a cheap, rapid, portable and easy to use filter paper based assay for the qualitative and quantitate analysis of acetone. Sodium alginate gel was loaded with the acetone specific optical signal probe, and subsequently coated onto filter paper surface to design portable colorimetric assays for acetone monitoring. The color of the paper sensor strip was observed to change from dark yellow to light yellowish in the presence of varying concentrations of acetone. Three different color analyzing models including RGB, HSV, and LAB were employed to probe the output optical signal, and their performance was compared in terms of better interpretation of the generated signal. The LAB model was found to provide better analytical figures of merit with a linear response for the acetone concentration ranging from 2.5 to 1500 ppm, and a limit of detection of 0.5 ppm. Furthermore, the specificity of the designed filter paper based sensor was demonstrated against different common interfering compounds. The results demonstrated the potential of our proposed filter paper based sensor as a novel tool for the analysis of acetone.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199978&type=printable |
| spellingShingle | Sajid Rauf Yaqeen Ali Sabir Hussain Fakhar Ullah Akhtar Hayat Design of a novel filter paper based construct for rapid analysis of acetone. PLoS ONE |
| title | Design of a novel filter paper based construct for rapid analysis of acetone. |
| title_full | Design of a novel filter paper based construct for rapid analysis of acetone. |
| title_fullStr | Design of a novel filter paper based construct for rapid analysis of acetone. |
| title_full_unstemmed | Design of a novel filter paper based construct for rapid analysis of acetone. |
| title_short | Design of a novel filter paper based construct for rapid analysis of acetone. |
| title_sort | design of a novel filter paper based construct for rapid analysis of acetone |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199978&type=printable |
| work_keys_str_mv | AT sajidrauf designofanovelfilterpaperbasedconstructforrapidanalysisofacetone AT yaqeenali designofanovelfilterpaperbasedconstructforrapidanalysisofacetone AT sabirhussain designofanovelfilterpaperbasedconstructforrapidanalysisofacetone AT fakharullah designofanovelfilterpaperbasedconstructforrapidanalysisofacetone AT akhtarhayat designofanovelfilterpaperbasedconstructforrapidanalysisofacetone |