Serum cytokine levels in patients with acute alcohol heart pathology

Aim. To investigate cardiohemodynamic parameters and serum cytokine levels in patients with severe alcohol intoxication (AI). Material and methods. In total, 100 patients with severe AI were examined. All participants underwent 24-hour electrocardiogram (ECG) monitoring, echocardiography (EchoCG), a...

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Main Authors: V. V. Gorbunov, A. V. Govorin, S. A. Alekseev
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2006-04-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1157
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author V. V. Gorbunov
A. V. Govorin
S. A. Alekseev
author_facet V. V. Gorbunov
A. V. Govorin
S. A. Alekseev
author_sort V. V. Gorbunov
collection DOAJ
description Aim. To investigate cardiohemodynamic parameters and serum cytokine levels in patients with severe alcohol intoxication (AI). Material and methods. In total, 100 patients with severe AI were examined. All participants underwent 24-hour electrocardiogram (ECG) monitoring, echocardiography (EchoCG), and measurement of serum pro-inflammatory cytokine levels . Results. In patients with severe AI, acute alcohol heart damage (AAHD) was diagnosed relatively often (31.4%). Among these individuals, EchoCG disturbances and increase in serum cytokine levels were maximal. Conclusion. In patients with AAHD, complicated by fatal arrhythmias, pro-inflammatory cytokine synthesis was increased, comparing to arrhythmia-free patients. Maximal cytokine concentration was registered in patients with systolic and/or diastolic left ventricular dysfunction.
format Article
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institution Kabale University
issn 1728-8800
2619-0125
language Russian
publishDate 2006-04-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-0ae5bfafcf024df790053988db085c932025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252006-04-01526467869Serum cytokine levels in patients with acute alcohol heart pathologyV. V. Gorbunov0A. V. Govorin1S. A. Alekseev2Chita State Medical Academy. ChitaChita State Medical Academy. ChitaChita State Medical Academy. ChitaAim. To investigate cardiohemodynamic parameters and serum cytokine levels in patients with severe alcohol intoxication (AI). Material and methods. In total, 100 patients with severe AI were examined. All participants underwent 24-hour electrocardiogram (ECG) monitoring, echocardiography (EchoCG), and measurement of serum pro-inflammatory cytokine levels . Results. In patients with severe AI, acute alcohol heart damage (AAHD) was diagnosed relatively often (31.4%). Among these individuals, EchoCG disturbances and increase in serum cytokine levels were maximal. Conclusion. In patients with AAHD, complicated by fatal arrhythmias, pro-inflammatory cytokine synthesis was increased, comparing to arrhythmia-free patients. Maximal cytokine concentration was registered in patients with systolic and/or diastolic left ventricular dysfunction.https://cardiovascular.elpub.ru/jour/article/view/1157acute alcohol heart damagecytokinescardiohemodynamics
spellingShingle V. V. Gorbunov
A. V. Govorin
S. A. Alekseev
Serum cytokine levels in patients with acute alcohol heart pathology
Кардиоваскулярная терапия и профилактика
acute alcohol heart damage
cytokines
cardiohemodynamics
title Serum cytokine levels in patients with acute alcohol heart pathology
title_full Serum cytokine levels in patients with acute alcohol heart pathology
title_fullStr Serum cytokine levels in patients with acute alcohol heart pathology
title_full_unstemmed Serum cytokine levels in patients with acute alcohol heart pathology
title_short Serum cytokine levels in patients with acute alcohol heart pathology
title_sort serum cytokine levels in patients with acute alcohol heart pathology
topic acute alcohol heart damage
cytokines
cardiohemodynamics
url https://cardiovascular.elpub.ru/jour/article/view/1157
work_keys_str_mv AT vvgorbunov serumcytokinelevelsinpatientswithacutealcoholheartpathology
AT avgovorin serumcytokinelevelsinpatientswithacutealcoholheartpathology
AT saalekseev serumcytokinelevelsinpatientswithacutealcoholheartpathology