Serum cytokine levels in patients with acute alcohol heart pathology

Aim. To investigate cardiohemodynamic parameters and serum cytokine levels in patients with severe alcohol intoxication (AI). Material and methods. In total, 100 patients with severe AI were examined. All participants underwent 24-hour electrocardiogram (ECG) monitoring, echocardiography (EchoCG), a...

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Bibliographic Details
Main Authors: V. V. Gorbunov, A. V. Govorin, S. A. Alekseev
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2006-04-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/1157
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Summary:Aim. To investigate cardiohemodynamic parameters and serum cytokine levels in patients with severe alcohol intoxication (AI). Material and methods. In total, 100 patients with severe AI were examined. All participants underwent 24-hour electrocardiogram (ECG) monitoring, echocardiography (EchoCG), and measurement of serum pro-inflammatory cytokine levels . Results. In patients with severe AI, acute alcohol heart damage (AAHD) was diagnosed relatively often (31.4%). Among these individuals, EchoCG disturbances and increase in serum cytokine levels were maximal. Conclusion. In patients with AAHD, complicated by fatal arrhythmias, pro-inflammatory cytokine synthesis was increased, comparing to arrhythmia-free patients. Maximal cytokine concentration was registered in patients with systolic and/or diastolic left ventricular dysfunction.
ISSN:1728-8800
2619-0125