Triterpenoids from Ganoderma lucidum inhibit cytochrome P450 enzymes interfering with the metabolic process of specific clinical drugs

Triterpenoids from Ganoderma lucidum inhibit cytochrome P450 enzymes interfering with the metabolic process of specific clinical drugs

BackgroundGanoderma lucidum (G. lucidum), which possesses various biological effects, has been widely used as traditional medicine and functional food in Asian countries, especially China. In consideration of its various biological effects on human healthcare, G. lucidum was usually used in combinat...

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Bibliographic Details
Main Authors: Dawei Li, Yuxin Lin, Xia Lv, Yuzhuo Wu, Chaoyan Han, Peng Cao, Guixin Zhang, Aijing Leng, Jian Zhou, Chao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
Ganoderma lucidum
functional food
CYP450s
lanostrane triterpenoid
drug-drug interactions
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1485209/full
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