Algal Active Ingredients and Their Involvement in Managing Diabetic Mellitus

Diabetes mellitus (DM) is becoming increasingly prominent, posing a serious threat to human health. Its prevalence is rising every year, and often affects young people. In the past few decades, research on marine algae has been recognized as a major field of drug discovery. Seaweed active substances...

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Main Authors: Aijun Tong, Dengwei Wang, Nan Jia, Ying Zheng, Yusong Qiu, Weichao Chen, Hesham R. El-Seed, Chao Zhao
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/13/11/904
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author Aijun Tong
Dengwei Wang
Nan Jia
Ying Zheng
Yusong Qiu
Weichao Chen
Hesham R. El-Seed
Chao Zhao
author_facet Aijun Tong
Dengwei Wang
Nan Jia
Ying Zheng
Yusong Qiu
Weichao Chen
Hesham R. El-Seed
Chao Zhao
author_sort Aijun Tong
collection DOAJ
description Diabetes mellitus (DM) is becoming increasingly prominent, posing a serious threat to human health. Its prevalence is rising every year, and often affects young people. In the past few decades, research on marine algae has been recognized as a major field of drug discovery. Seaweed active substances, including algal polysaccharides, algal polyphenols, algal unsaturated fatty acids, and algal dietary fiber, have unique biological activities. This article reviews the effects and mechanisms of the types, structures, and compositions of seaweed on inhibiting glucose and lipid metabolism disorders, with a focus on the inhibitory effect of active substances on blood glucose reduction. The aim is to provide a basis for the development of seaweed active substance hypoglycemic drugs.
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spelling doaj-art-0ae48190979f4bb29322087c90d54ec22025-08-20T02:08:02ZengMDPI AGBiology2079-77372024-11-01131190410.3390/biology13110904Algal Active Ingredients and Their Involvement in Managing Diabetic MellitusAijun Tong0Dengwei Wang1Nan Jia2Ying Zheng3Yusong Qiu4Weichao Chen5Hesham R. El-Seed6Chao Zhao7College of Tea and Food Science, Wuyi University, Wuyishan 354300, ChinaDepartment of Chronic and Noncommunicable Disease Control and Prevention, Fujian Provincial Center for Disease Control and Prevention, Fuzhou 350012, ChinaState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaDepartment of Chemistry, Faculty of Science, Islamic University of Madinah, Madinah 42351, Saudi ArabiaState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaDiabetes mellitus (DM) is becoming increasingly prominent, posing a serious threat to human health. Its prevalence is rising every year, and often affects young people. In the past few decades, research on marine algae has been recognized as a major field of drug discovery. Seaweed active substances, including algal polysaccharides, algal polyphenols, algal unsaturated fatty acids, and algal dietary fiber, have unique biological activities. This article reviews the effects and mechanisms of the types, structures, and compositions of seaweed on inhibiting glucose and lipid metabolism disorders, with a focus on the inhibitory effect of active substances on blood glucose reduction. The aim is to provide a basis for the development of seaweed active substance hypoglycemic drugs.https://www.mdpi.com/2079-7737/13/11/904algaeactive substanceshyperglycemia
spellingShingle Aijun Tong
Dengwei Wang
Nan Jia
Ying Zheng
Yusong Qiu
Weichao Chen
Hesham R. El-Seed
Chao Zhao
Algal Active Ingredients and Their Involvement in Managing Diabetic Mellitus
Biology
algae
active substances
hyperglycemia
title Algal Active Ingredients and Their Involvement in Managing Diabetic Mellitus
title_full Algal Active Ingredients and Their Involvement in Managing Diabetic Mellitus
title_fullStr Algal Active Ingredients and Their Involvement in Managing Diabetic Mellitus
title_full_unstemmed Algal Active Ingredients and Their Involvement in Managing Diabetic Mellitus
title_short Algal Active Ingredients and Their Involvement in Managing Diabetic Mellitus
title_sort algal active ingredients and their involvement in managing diabetic mellitus
topic algae
active substances
hyperglycemia
url https://www.mdpi.com/2079-7737/13/11/904
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