Arthritis alleviation: unveiling the potential in Abrus precatorius macerated oil
Aim: This study endeavors to explore the anti-arthritic effects of macerated oil derived from the plant's aerial parts. Methods: The macerated oil was prepared using maceration in coconut oil, and its phytochemical composition was elucidated using GC-MS. To assess its anti-arthritic activity, i...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Future Science OA |
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| Online Access: | https://www.tandfonline.com/doi/10.2144/fsoa-2023-0248 |
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| author | Sukanya Vijayan Thirumal Margesan |
| author_facet | Sukanya Vijayan Thirumal Margesan |
| author_sort | Sukanya Vijayan |
| collection | DOAJ |
| description | Aim: This study endeavors to explore the anti-arthritic effects of macerated oil derived from the plant's aerial parts. Methods: The macerated oil was prepared using maceration in coconut oil, and its phytochemical composition was elucidated using GC-MS. To assess its anti-arthritic activity, in-vitro studies were conducted using various assays. Results & conclusion: The macerated oil showed better antioxidant and anti-arthritic potential by in-vitro investigations. Molecular docking studies elucidated potential binding interactions between specific constituents of the oil and critical molecular targets implicated in the pathogenesis of arthritis, further substantiating its therapeutic potential. The results demonstrated that Abrus precatorius macerated oil could ameliorate arthritis severity in a dose-dependent manner. |
| format | Article |
| id | doaj-art-0ae22cc4dd2f4d3db4c61ca64c0b86bc |
| institution | DOAJ |
| issn | 2056-5623 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Future Science OA |
| spelling | doaj-art-0ae22cc4dd2f4d3db4c61ca64c0b86bc2025-08-20T03:11:55ZengTaylor & Francis GroupFuture Science OA2056-56232024-12-0110110.2144/fsoa-2023-0248Arthritis alleviation: unveiling the potential in Abrus precatorius macerated oilSukanya Vijayan0Thirumal Margesan1Department of Pharmacognosy, SRM College of Pharmacy, SRM Institute of Science & Technology, Kattankulathur, 603203, Chengalpattu, Tamil Nadu, IndiaDepartment of Pharmacognosy, SRM College of Pharmacy, SRM Institute of Science & Technology, Kattankulathur, 603203, Chengalpattu, Tamil Nadu, IndiaAim: This study endeavors to explore the anti-arthritic effects of macerated oil derived from the plant's aerial parts. Methods: The macerated oil was prepared using maceration in coconut oil, and its phytochemical composition was elucidated using GC-MS. To assess its anti-arthritic activity, in-vitro studies were conducted using various assays. Results & conclusion: The macerated oil showed better antioxidant and anti-arthritic potential by in-vitro investigations. Molecular docking studies elucidated potential binding interactions between specific constituents of the oil and critical molecular targets implicated in the pathogenesis of arthritis, further substantiating its therapeutic potential. The results demonstrated that Abrus precatorius macerated oil could ameliorate arthritis severity in a dose-dependent manner.https://www.tandfonline.com/doi/10.2144/fsoa-2023-0248Abrus precatoriusanti-arthriticantioxidantmacerated oilmolecular docking |
| spellingShingle | Sukanya Vijayan Thirumal Margesan Arthritis alleviation: unveiling the potential in Abrus precatorius macerated oil Future Science OA Abrus precatorius anti-arthritic antioxidant macerated oil molecular docking |
| title | Arthritis alleviation: unveiling the potential in Abrus precatorius macerated oil |
| title_full | Arthritis alleviation: unveiling the potential in Abrus precatorius macerated oil |
| title_fullStr | Arthritis alleviation: unveiling the potential in Abrus precatorius macerated oil |
| title_full_unstemmed | Arthritis alleviation: unveiling the potential in Abrus precatorius macerated oil |
| title_short | Arthritis alleviation: unveiling the potential in Abrus precatorius macerated oil |
| title_sort | arthritis alleviation unveiling the potential in abrus precatorius macerated oil |
| topic | Abrus precatorius anti-arthritic antioxidant macerated oil molecular docking |
| url | https://www.tandfonline.com/doi/10.2144/fsoa-2023-0248 |
| work_keys_str_mv | AT sukanyavijayan arthritisalleviationunveilingthepotentialinabrusprecatoriusmaceratedoil AT thirumalmargesan arthritisalleviationunveilingthepotentialinabrusprecatoriusmaceratedoil |