Sulfasalazine efficacy and tolerability in rheumatic diseases
Sulfasalazine is one of the main disease modifying drugs for the treatment of chronic inflammatory joint and spine diseases. The article describes mechanism of action of sulfasalazine and its main metabolites. Detailed information about anti-inflammatory and immunosuppressive action of the drug is p...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2005-08-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/755 |
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| _version_ | 1849240348718530560 |
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| author | V. V. Badokin |
| author_facet | V. V. Badokin |
| author_sort | V. V. Badokin |
| collection | DOAJ |
| description | Sulfasalazine is one of the main disease modifying drugs for the treatment of chronic inflammatory joint and spine diseases. The article describes mechanism of action of sulfasalazine and its main metabolites. Detailed information about anti-inflammatory and immunosuppressive action of the drug is presented. Results of many studies of sulfasalazine efficacy in rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and reactive arthritis are discussed from the evidence based medicine point of view. Data on sulfasalazine tolerability and safety are presented with separate discussion of hypersensitivity and dose-dependent adverse reactions so as their treatment and prophylaxis. |
| format | Article |
| id | doaj-art-0ad5cf1774b543dda3c2296f2f984a7c |
| institution | Kabale University |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2005-08-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-0ad5cf1774b543dda3c2296f2f984a7c2025-08-20T04:00:38ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922005-08-01434475210.14412/1995-4484-2005-617695Sulfasalazine efficacy and tolerability in rheumatic diseasesV. V. BadokinSulfasalazine is one of the main disease modifying drugs for the treatment of chronic inflammatory joint and spine diseases. The article describes mechanism of action of sulfasalazine and its main metabolites. Detailed information about anti-inflammatory and immunosuppressive action of the drug is presented. Results of many studies of sulfasalazine efficacy in rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and reactive arthritis are discussed from the evidence based medicine point of view. Data on sulfasalazine tolerability and safety are presented with separate discussion of hypersensitivity and dose-dependent adverse reactions so as their treatment and prophylaxis.https://rsp.mediar-press.net/rsp/article/view/755sulfasalazinedisease modifying drugsrheumatoid arthritisseronegative spondyloarthritides |
| spellingShingle | V. V. Badokin Sulfasalazine efficacy and tolerability in rheumatic diseases Научно-практическая ревматология sulfasalazine disease modifying drugs rheumatoid arthritis seronegative spondyloarthritides |
| title | Sulfasalazine efficacy and tolerability in rheumatic diseases |
| title_full | Sulfasalazine efficacy and tolerability in rheumatic diseases |
| title_fullStr | Sulfasalazine efficacy and tolerability in rheumatic diseases |
| title_full_unstemmed | Sulfasalazine efficacy and tolerability in rheumatic diseases |
| title_short | Sulfasalazine efficacy and tolerability in rheumatic diseases |
| title_sort | sulfasalazine efficacy and tolerability in rheumatic diseases |
| topic | sulfasalazine disease modifying drugs rheumatoid arthritis seronegative spondyloarthritides |
| url | https://rsp.mediar-press.net/rsp/article/view/755 |
| work_keys_str_mv | AT vvbadokin sulfasalazineefficacyandtolerabilityinrheumaticdiseases |