Polypharmacy driven synergistic toxicities in elderly breast cancer chemotherapy drug management and adverse drug reactions: a mini review
Breast cancer is increasingly diagnosed in older women (median age ≈63 years), and chemotherapy outcomes are clouded by a polypharmacy landscape—defined here as ≥5 concurrent medications—that magnifies toxicity beyond single-agent expectations. Prospective geriatric-oncology cohorts reveal a median...
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| Main Authors: | Xiran Wang, Jin Yang, Jieying Zhang, Hong Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1654353/full |
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