Prevalence of Age-Associated Testosterone Deficiency Syndrome in Indian Population
Testosterone deficiency syndrome (TDS) is a gradual age-related phenomenon that occurs in a large proportion of the aging male population. This current prospective study was done with the objective to estimate the prevalence of age-associated TDS in India and its clinical profile. A total of 800 mal...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
|
| Series: | Advances in Urology |
| Online Access: | http://dx.doi.org/10.1155/2019/2468926 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850232470649176064 |
|---|---|
| author | Ghanendra Kumar Yadav Mrinal Pahwa Mahendra Singh Vipin Tyagi Sudhir Chadha |
| author_facet | Ghanendra Kumar Yadav Mrinal Pahwa Mahendra Singh Vipin Tyagi Sudhir Chadha |
| author_sort | Ghanendra Kumar Yadav |
| collection | DOAJ |
| description | Testosterone deficiency syndrome (TDS) is a gradual age-related phenomenon that occurs in a large proportion of the aging male population. This current prospective study was done with the objective to estimate the prevalence of age-associated TDS in India and its clinical profile. A total of 800 male patients aged ≥40 year were approached to participate in the study. A brief history and focused examination was done. Based on our exclusion criteria, 55 patients were excluded. Androgen deficiency in aging male (ADAM) questionnaire was administered to all remaining 745 patients. Out of these 745 patients, ADAM-positive (symptomatic TDS) patients were found to be 359 and enrolled in the study. In all ADAM-positive patients, serum testosterone levels were measured. Prevalence of symptomatic TDS in study population was found to be 48.18%. Mean total and free testosterone level of symptomatic TDS population were 3.287 ± 1.494 ng/ml (1.12–9.61) and 7.476 ± 2.902 pg/ml (2.18–21.76), respectively. Prevalence of biochemically confirmed TDS among symptomatic TDS population was 60.17%. Prevalence of TDS increases progressively with each decade of life (p=0.034). Prevalence was higher in patients with diabetes, hypertension, coronary artery disease, obesity, and metabolic syndrome. TDS is a real phenomenon with a prevalence of 28.99% in our study population. |
| format | Article |
| id | doaj-art-0acff46eb50f42ae90b7d619bc929221 |
| institution | OA Journals |
| issn | 1687-6369 1687-6377 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Urology |
| spelling | doaj-art-0acff46eb50f42ae90b7d619bc9292212025-08-20T02:03:12ZengWileyAdvances in Urology1687-63691687-63772019-01-01201910.1155/2019/24689262468926Prevalence of Age-Associated Testosterone Deficiency Syndrome in Indian PopulationGhanendra Kumar Yadav0Mrinal Pahwa1Mahendra Singh2Vipin Tyagi3Sudhir Chadha4Department of Urology, Sir Ganga Ram Hospital, New Delhi, IndiaDepartment of Urology, Sir Ganga Ram Hospital, New Delhi, IndiaDepartment of Urology, Sir Ganga Ram Hospital, New Delhi, IndiaDepartment of Urology, Sir Ganga Ram Hospital, New Delhi, IndiaDepartment of Urology, Sir Ganga Ram Hospital, New Delhi, IndiaTestosterone deficiency syndrome (TDS) is a gradual age-related phenomenon that occurs in a large proportion of the aging male population. This current prospective study was done with the objective to estimate the prevalence of age-associated TDS in India and its clinical profile. A total of 800 male patients aged ≥40 year were approached to participate in the study. A brief history and focused examination was done. Based on our exclusion criteria, 55 patients were excluded. Androgen deficiency in aging male (ADAM) questionnaire was administered to all remaining 745 patients. Out of these 745 patients, ADAM-positive (symptomatic TDS) patients were found to be 359 and enrolled in the study. In all ADAM-positive patients, serum testosterone levels were measured. Prevalence of symptomatic TDS in study population was found to be 48.18%. Mean total and free testosterone level of symptomatic TDS population were 3.287 ± 1.494 ng/ml (1.12–9.61) and 7.476 ± 2.902 pg/ml (2.18–21.76), respectively. Prevalence of biochemically confirmed TDS among symptomatic TDS population was 60.17%. Prevalence of TDS increases progressively with each decade of life (p=0.034). Prevalence was higher in patients with diabetes, hypertension, coronary artery disease, obesity, and metabolic syndrome. TDS is a real phenomenon with a prevalence of 28.99% in our study population.http://dx.doi.org/10.1155/2019/2468926 |
| spellingShingle | Ghanendra Kumar Yadav Mrinal Pahwa Mahendra Singh Vipin Tyagi Sudhir Chadha Prevalence of Age-Associated Testosterone Deficiency Syndrome in Indian Population Advances in Urology |
| title | Prevalence of Age-Associated Testosterone Deficiency Syndrome in Indian Population |
| title_full | Prevalence of Age-Associated Testosterone Deficiency Syndrome in Indian Population |
| title_fullStr | Prevalence of Age-Associated Testosterone Deficiency Syndrome in Indian Population |
| title_full_unstemmed | Prevalence of Age-Associated Testosterone Deficiency Syndrome in Indian Population |
| title_short | Prevalence of Age-Associated Testosterone Deficiency Syndrome in Indian Population |
| title_sort | prevalence of age associated testosterone deficiency syndrome in indian population |
| url | http://dx.doi.org/10.1155/2019/2468926 |
| work_keys_str_mv | AT ghanendrakumaryadav prevalenceofageassociatedtestosteronedeficiencysyndromeinindianpopulation AT mrinalpahwa prevalenceofageassociatedtestosteronedeficiencysyndromeinindianpopulation AT mahendrasingh prevalenceofageassociatedtestosteronedeficiencysyndromeinindianpopulation AT vipintyagi prevalenceofageassociatedtestosteronedeficiencysyndromeinindianpopulation AT sudhirchadha prevalenceofageassociatedtestosteronedeficiencysyndromeinindianpopulation |