Biofilms by bacterial human pathogens:Clinical relevance - development, composition and regulation - therapeutical strategies
Notably, bacterial biofilm formation is increasingly recog-nized as a passive virulence factor facilitating many infec-tious disease processes. In this review we will focus on bacterial biofilms formed by human pathogens and high-light their relevance for diverse diseases. Along biofilm composition...
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| Format: | Article |
| Language: | English |
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Shared Science Publishers OG
2021-02-01
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| Series: | Microbial Cell |
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| Online Access: | http://microbialcell.com/researcharticles/2021a-schulze-microbial-cell/ |
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| author | Adina Schulze Fabian Mitterer Joao P. Pombo Stefan Schild |
| author_facet | Adina Schulze Fabian Mitterer Joao P. Pombo Stefan Schild |
| author_sort | Adina Schulze |
| collection | DOAJ |
| description | Notably, bacterial biofilm formation is increasingly recog-nized as a passive virulence factor facilitating many infec-tious disease processes. In this review we will focus on bacterial biofilms formed by human pathogens and high-light their relevance for diverse diseases. Along biofilm composition and regulation emphasis is laid on the inten-sively studied biofilms of Vibrio cholerae, Pseudomonas aeruginosa and Staphylococcus spp., which are commonly used as biofilm model organisms and therefore contribute to our general understanding of bacterial biofilm (patho-)physiology. Finally, therapeutical intervention strategies targeting biofilms will be discussed. |
| format | Article |
| id | doaj-art-0acc69b413a748ac9a6c95fc65f79ff4 |
| institution | DOAJ |
| issn | 2311-2638 |
| language | English |
| publishDate | 2021-02-01 |
| publisher | Shared Science Publishers OG |
| record_format | Article |
| series | Microbial Cell |
| spelling | doaj-art-0acc69b413a748ac9a6c95fc65f79ff42025-08-20T02:53:21ZengShared Science Publishers OGMicrobial Cell2311-26382021-02-0182285610.15698/mic2021.02.741Biofilms by bacterial human pathogens:Clinical relevance - development, composition and regulation - therapeutical strategiesAdina Schulze0Fabian Mitterer1Joao P. Pombo2Stefan Schild3Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria.Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria.Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria.Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria.Notably, bacterial biofilm formation is increasingly recog-nized as a passive virulence factor facilitating many infec-tious disease processes. In this review we will focus on bacterial biofilms formed by human pathogens and high-light their relevance for diverse diseases. Along biofilm composition and regulation emphasis is laid on the inten-sively studied biofilms of Vibrio cholerae, Pseudomonas aeruginosa and Staphylococcus spp., which are commonly used as biofilm model organisms and therefore contribute to our general understanding of bacterial biofilm (patho-)physiology. Finally, therapeutical intervention strategies targeting biofilms will be discussed.http://microbialcell.com/researcharticles/2021a-schulze-microbial-cell/biofilm-associated diseasenosocomial infectionsvibrio choleraepseudomonas aeruginosastaphylococcitreatmentbiofilm |
| spellingShingle | Adina Schulze Fabian Mitterer Joao P. Pombo Stefan Schild Biofilms by bacterial human pathogens:Clinical relevance - development, composition and regulation - therapeutical strategies Microbial Cell biofilm-associated disease nosocomial infections vibrio cholerae pseudomonas aeruginosa staphylococci treatment biofilm |
| title | Biofilms by bacterial human pathogens:Clinical relevance - development, composition and regulation - therapeutical strategies |
| title_full | Biofilms by bacterial human pathogens:Clinical relevance - development, composition and regulation - therapeutical strategies |
| title_fullStr | Biofilms by bacterial human pathogens:Clinical relevance - development, composition and regulation - therapeutical strategies |
| title_full_unstemmed | Biofilms by bacterial human pathogens:Clinical relevance - development, composition and regulation - therapeutical strategies |
| title_short | Biofilms by bacterial human pathogens:Clinical relevance - development, composition and regulation - therapeutical strategies |
| title_sort | biofilms by bacterial human pathogens clinical relevance development composition and regulation therapeutical strategies |
| topic | biofilm-associated disease nosocomial infections vibrio cholerae pseudomonas aeruginosa staphylococci treatment biofilm |
| url | http://microbialcell.com/researcharticles/2021a-schulze-microbial-cell/ |
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