Counter mucosal incision with Zenker's peroral endoscopic myotomy: an innovative approach for mucosal decompression in Zenker’s diverticulum and mucosal webs

Background and Aims: Zenker’s diverticulum (ZD) is a pouch of the mucosa arising from the Killian triangle. Any size of symptomatic ZD or medium to large (2-3 cm or more) ZD needs intervention. Zenker's peroral endoscopic myotomy (Z-POEM) is the ideal first-line therapy for making the reliable...

Full description

Saved in:
Bibliographic Details
Main Authors: Boldbaatar Gantuya, MD, PhD, Haruhiro Inoue, MD, PhD, Kazuki Yamamoto, MD, PhD, Ippei Tanaka, MD, Yohei Nishikawa, MD, Kei Ushikubo, MD, Mayo Tanabe, MD
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:VideoGIE
Online Access:http://www.sciencedirect.com/science/article/pii/S2468448125001201
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849390140737191936
author Boldbaatar Gantuya, MD, PhD
Haruhiro Inoue, MD, PhD
Kazuki Yamamoto, MD, PhD
Ippei Tanaka, MD
Yohei Nishikawa, MD
Kei Ushikubo, MD
Mayo Tanabe, MD
author_facet Boldbaatar Gantuya, MD, PhD
Haruhiro Inoue, MD, PhD
Kazuki Yamamoto, MD, PhD
Ippei Tanaka, MD
Yohei Nishikawa, MD
Kei Ushikubo, MD
Mayo Tanabe, MD
author_sort Boldbaatar Gantuya, MD, PhD
collection DOAJ
description Background and Aims: Zenker’s diverticulum (ZD) is a pouch of the mucosa arising from the Killian triangle. Any size of symptomatic ZD or medium to large (2-3 cm or more) ZD needs intervention. Zenker's peroral endoscopic myotomy (Z-POEM) is the ideal first-line therapy for making the reliable myotomy. We aimed to demonstrate the latest Z-POEM techniques and counter mucosal incision (CMI) for a patient with larger-sized ZD and pre-existing esophageal mucosal webs near ZD. Methods: The CMI technique recently was developed by our hospital for antireflux intervention. It is a novel tension-relief technique of the mucosal plasty for enhancing closure stability. This time we performed esophageal mucosal incision on the opposite side of the Z-POEM defect closure part to relieve the mucosal tension and alleviate a postoperative stricture resulting from the tight clip closure in the background of the stiff surrounding mucosa and webs near the ZD. Results: We obtained complete eradication of ZD pouch without creating a stricture. Conclusions: CMI is the ideal approach for preventing a stricture related to the use of tight clip closure of the Z-POEM for a larger-sized ZD with a background of the surrounding mucosal webs.
format Article
id doaj-art-0acbba167b2a40c0a4d58bffbcb07980
institution Kabale University
issn 2468-4481
language English
publishDate 2025-09-01
publisher Elsevier
record_format Article
series VideoGIE
spelling doaj-art-0acbba167b2a40c0a4d58bffbcb079802025-08-20T03:41:46ZengElsevierVideoGIE2468-44812025-09-0110944344710.1016/j.vgie.2025.04.011Counter mucosal incision with Zenker's peroral endoscopic myotomy: an innovative approach for mucosal decompression in Zenker’s diverticulum and mucosal websBoldbaatar Gantuya, MD, PhD0Haruhiro Inoue, MD, PhD1Kazuki Yamamoto, MD, PhD2Ippei Tanaka, MD3Yohei Nishikawa, MD4Kei Ushikubo, MD5Mayo Tanabe, MD6Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan; Department of Gastroenterology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia; Endoscopy Unit, Mongolia Japan Hospital of Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia; Corresponding author: Boldbaatar Gantuya, MD, PhD, Digestive Diseases Center, Showa University Koto Toyosu Hospital, 5-1-38 Toyosu, Koto-ku, Tokyo 135-8577, Japan.Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, JapanDigestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, JapanDigestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, JapanDigestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, JapanDigestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, JapanDigestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, JapanBackground and Aims: Zenker’s diverticulum (ZD) is a pouch of the mucosa arising from the Killian triangle. Any size of symptomatic ZD or medium to large (2-3 cm or more) ZD needs intervention. Zenker's peroral endoscopic myotomy (Z-POEM) is the ideal first-line therapy for making the reliable myotomy. We aimed to demonstrate the latest Z-POEM techniques and counter mucosal incision (CMI) for a patient with larger-sized ZD and pre-existing esophageal mucosal webs near ZD. Methods: The CMI technique recently was developed by our hospital for antireflux intervention. It is a novel tension-relief technique of the mucosal plasty for enhancing closure stability. This time we performed esophageal mucosal incision on the opposite side of the Z-POEM defect closure part to relieve the mucosal tension and alleviate a postoperative stricture resulting from the tight clip closure in the background of the stiff surrounding mucosa and webs near the ZD. Results: We obtained complete eradication of ZD pouch without creating a stricture. Conclusions: CMI is the ideal approach for preventing a stricture related to the use of tight clip closure of the Z-POEM for a larger-sized ZD with a background of the surrounding mucosal webs.http://www.sciencedirect.com/science/article/pii/S2468448125001201
spellingShingle Boldbaatar Gantuya, MD, PhD
Haruhiro Inoue, MD, PhD
Kazuki Yamamoto, MD, PhD
Ippei Tanaka, MD
Yohei Nishikawa, MD
Kei Ushikubo, MD
Mayo Tanabe, MD
Counter mucosal incision with Zenker's peroral endoscopic myotomy: an innovative approach for mucosal decompression in Zenker’s diverticulum and mucosal webs
VideoGIE
title Counter mucosal incision with Zenker's peroral endoscopic myotomy: an innovative approach for mucosal decompression in Zenker’s diverticulum and mucosal webs
title_full Counter mucosal incision with Zenker's peroral endoscopic myotomy: an innovative approach for mucosal decompression in Zenker’s diverticulum and mucosal webs
title_fullStr Counter mucosal incision with Zenker's peroral endoscopic myotomy: an innovative approach for mucosal decompression in Zenker’s diverticulum and mucosal webs
title_full_unstemmed Counter mucosal incision with Zenker's peroral endoscopic myotomy: an innovative approach for mucosal decompression in Zenker’s diverticulum and mucosal webs
title_short Counter mucosal incision with Zenker's peroral endoscopic myotomy: an innovative approach for mucosal decompression in Zenker’s diverticulum and mucosal webs
title_sort counter mucosal incision with zenker s peroral endoscopic myotomy an innovative approach for mucosal decompression in zenker s diverticulum and mucosal webs
url http://www.sciencedirect.com/science/article/pii/S2468448125001201
work_keys_str_mv AT boldbaatargantuyamdphd countermucosalincisionwithzenkersperoralendoscopicmyotomyaninnovativeapproachformucosaldecompressioninzenkersdiverticulumandmucosalwebs
AT haruhiroinouemdphd countermucosalincisionwithzenkersperoralendoscopicmyotomyaninnovativeapproachformucosaldecompressioninzenkersdiverticulumandmucosalwebs
AT kazukiyamamotomdphd countermucosalincisionwithzenkersperoralendoscopicmyotomyaninnovativeapproachformucosaldecompressioninzenkersdiverticulumandmucosalwebs
AT ippeitanakamd countermucosalincisionwithzenkersperoralendoscopicmyotomyaninnovativeapproachformucosaldecompressioninzenkersdiverticulumandmucosalwebs
AT yoheinishikawamd countermucosalincisionwithzenkersperoralendoscopicmyotomyaninnovativeapproachformucosaldecompressioninzenkersdiverticulumandmucosalwebs
AT keiushikubomd countermucosalincisionwithzenkersperoralendoscopicmyotomyaninnovativeapproachformucosaldecompressioninzenkersdiverticulumandmucosalwebs
AT mayotanabemd countermucosalincisionwithzenkersperoralendoscopicmyotomyaninnovativeapproachformucosaldecompressioninzenkersdiverticulumandmucosalwebs