Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report
The mortality of pulmonary embolism in children is high, and there is no standardized treatment protocol. We present a case of successful treatment of Mycoplasma pneumoniae (M pneumoniae) with pulmonary embolism in a child using rivaroxaban and doxycycline, thereby exploring a more appropriate treat...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2025.1449493/full |
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| author | Fang Xiaoqian Lu Hemin |
| author_facet | Fang Xiaoqian Lu Hemin |
| author_sort | Fang Xiaoqian |
| collection | DOAJ |
| description | The mortality of pulmonary embolism in children is high, and there is no standardized treatment protocol. We present a case of successful treatment of Mycoplasma pneumoniae (M pneumoniae) with pulmonary embolism in a child using rivaroxaban and doxycycline, thereby exploring a more appropriate treatment option. A 10-year-old male presented with fever, cough, and chest pain as the main symptoms. M pneumoniae polymerase chain reaction of bronchoalveolar lavage fluid was positive, and computed tomography angiography indicated pulmonary embolism. Azithromycin, doxycycline, and piperacillin-tazobactam were administered sequentially for infection control, while methylprednisolone was given to control inflammation and heparin and rivaroxaban for sequential treatment, resulting in a satisfactory recovery. |
| format | Article |
| id | doaj-art-0ac5c2d7709a4548a0719128be0b269f |
| institution | Kabale University |
| issn | 2296-2360 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj-art-0ac5c2d7709a4548a0719128be0b269f2025-02-12T07:26:09ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-02-011310.3389/fped.2025.14494931449493Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case reportFang XiaoqianLu HeminThe mortality of pulmonary embolism in children is high, and there is no standardized treatment protocol. We present a case of successful treatment of Mycoplasma pneumoniae (M pneumoniae) with pulmonary embolism in a child using rivaroxaban and doxycycline, thereby exploring a more appropriate treatment option. A 10-year-old male presented with fever, cough, and chest pain as the main symptoms. M pneumoniae polymerase chain reaction of bronchoalveolar lavage fluid was positive, and computed tomography angiography indicated pulmonary embolism. Azithromycin, doxycycline, and piperacillin-tazobactam were administered sequentially for infection control, while methylprednisolone was given to control inflammation and heparin and rivaroxaban for sequential treatment, resulting in a satisfactory recovery.https://www.frontiersin.org/articles/10.3389/fped.2025.1449493/fullmycoplasmapulmonary embolismrivaroxabandoxycyclinecase report |
| spellingShingle | Fang Xiaoqian Lu Hemin Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report Frontiers in Pediatrics mycoplasma pulmonary embolism rivaroxaban doxycycline case report |
| title | Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report |
| title_full | Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report |
| title_fullStr | Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report |
| title_full_unstemmed | Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report |
| title_short | Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report |
| title_sort | successful rivaroxaban and doxycycline therapy for mycoplasma pneumonia with pulmonary embolism in children a case report |
| topic | mycoplasma pulmonary embolism rivaroxaban doxycycline case report |
| url | https://www.frontiersin.org/articles/10.3389/fped.2025.1449493/full |
| work_keys_str_mv | AT fangxiaoqian successfulrivaroxabananddoxycyclinetherapyformycoplasmapneumoniawithpulmonaryembolisminchildrenacasereport AT luhemin successfulrivaroxabananddoxycyclinetherapyformycoplasmapneumoniawithpulmonaryembolisminchildrenacasereport |