Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report

The mortality of pulmonary embolism in children is high, and there is no standardized treatment protocol. We present a case of successful treatment of Mycoplasma pneumoniae (M pneumoniae) with pulmonary embolism in a child using rivaroxaban and doxycycline, thereby exploring a more appropriate treat...

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Bibliographic Details
Main Authors: Fang Xiaoqian, Lu Hemin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1449493/full
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Summary:The mortality of pulmonary embolism in children is high, and there is no standardized treatment protocol. We present a case of successful treatment of Mycoplasma pneumoniae (M pneumoniae) with pulmonary embolism in a child using rivaroxaban and doxycycline, thereby exploring a more appropriate treatment option. A 10-year-old male presented with fever, cough, and chest pain as the main symptoms. M pneumoniae polymerase chain reaction of bronchoalveolar lavage fluid was positive, and computed tomography angiography indicated pulmonary embolism. Azithromycin, doxycycline, and piperacillin-tazobactam were administered sequentially for infection control, while methylprednisolone was given to control inflammation and heparin and rivaroxaban for sequential treatment, resulting in a satisfactory recovery.
ISSN:2296-2360