Review of antibiotic-resistant bacteria and antibiotic resistance genes within the one health framework

Background: The interdisciplinary One Health (OH) approach recognizes that human, animal, and environmental health are all interconnected. Its ultimate goal is to promote optimal health for all through the exploration of these relationships. Antibiotic resistance (AR) is a public health challenge th...

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Main Authors: Ayodele Oluwaseun Ajayi, Adebowale Toba Odeyemi, Olajide Joseph Akinjogunla, Akinwole Babafenwa Adeyeye, Ibiwumi Ayo-ajayi
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Infection Ecology & Epidemiology
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Online Access:https://www.tandfonline.com/doi/10.1080/20008686.2024.2312953
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author Ayodele Oluwaseun Ajayi
Adebowale Toba Odeyemi
Olajide Joseph Akinjogunla
Akinwole Babafenwa Adeyeye
Ibiwumi Ayo-ajayi
author_facet Ayodele Oluwaseun Ajayi
Adebowale Toba Odeyemi
Olajide Joseph Akinjogunla
Akinwole Babafenwa Adeyeye
Ibiwumi Ayo-ajayi
author_sort Ayodele Oluwaseun Ajayi
collection DOAJ
description Background: The interdisciplinary One Health (OH) approach recognizes that human, animal, and environmental health are all interconnected. Its ultimate goal is to promote optimal health for all through the exploration of these relationships. Antibiotic resistance (AR) is a public health challenge that has been primarily addressed within the context of human health and clinical settings. However, it has become increasingly evident that antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) that confer resistance are transmitted and circulated within humans, animals, and the environment. Therefore, to effectively address this issue, antibiotic resistance must also be considered an environmental and livestock/wildlife problem.Objective: This review was carried out to provide a broad overview of the existence of ARB and ARGs in One Health settings.Methods: Relevant studies that placed emphasis on ARB and ARGs were reviewed and key findings were accessed that illustrate the importance of One Health as a measure to tackle growing public and environmental threats.Results: In this review, we delve into the complex interplay of the three components of OH in relation to ARB and ARGs. Antibiotics used in animal husbandry and plants to promote growth, treat, and prevent infectious diseases lead to the development of antibiotic-resistant bacteria in animals. These bacteria are transmitted from animals to humans through food and environmental exposure. The environment plays a critical role in the circulation and persistence of antibiotic-resistant bacteria and genes, posing a significant threat to human and animal health. This article also highlights how ARGs are spread in the environment through the transfer of genetic material between bacteria. This transfer can occur naturally or through human activities such as the use of antibiotics in agriculture and waste management practices.Conclusion: It is important to integrate the One Health approach into the public health system to effectively tackle the emergence and spread of ARB and genes that code for resistance to different antibiotics.
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spelling doaj-art-0ac34727da564bad952400ce76fadf662025-08-20T02:07:23ZengTaylor & Francis GroupInfection Ecology & Epidemiology2000-86862024-12-0114110.1080/20008686.2024.2312953Review of antibiotic-resistant bacteria and antibiotic resistance genes within the one health frameworkAyodele Oluwaseun Ajayi0Adebowale Toba Odeyemi1Olajide Joseph Akinjogunla2Akinwole Babafenwa Adeyeye3Ibiwumi Ayo-ajayi4Department of Microbiology, Federal University Oye Ekiti, Ekiti State, NigeriaDepartment of Microbiology, Landmark University SDG Groups 2 and 3, Omu-Aran, Kwara State, NigeriaDepartment of Microbiology, Faculty of Science, University of Uyo, Akwa-Ibom State, NigeriaDepartment of Microbiology, Federal University Oye Ekiti, Ekiti State, NigeriaDepartment of Computer Science, Afe Babalola University, Ado Ekiti, Ekiti State, NigeriaBackground: The interdisciplinary One Health (OH) approach recognizes that human, animal, and environmental health are all interconnected. Its ultimate goal is to promote optimal health for all through the exploration of these relationships. Antibiotic resistance (AR) is a public health challenge that has been primarily addressed within the context of human health and clinical settings. However, it has become increasingly evident that antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) that confer resistance are transmitted and circulated within humans, animals, and the environment. Therefore, to effectively address this issue, antibiotic resistance must also be considered an environmental and livestock/wildlife problem.Objective: This review was carried out to provide a broad overview of the existence of ARB and ARGs in One Health settings.Methods: Relevant studies that placed emphasis on ARB and ARGs were reviewed and key findings were accessed that illustrate the importance of One Health as a measure to tackle growing public and environmental threats.Results: In this review, we delve into the complex interplay of the three components of OH in relation to ARB and ARGs. Antibiotics used in animal husbandry and plants to promote growth, treat, and prevent infectious diseases lead to the development of antibiotic-resistant bacteria in animals. These bacteria are transmitted from animals to humans through food and environmental exposure. The environment plays a critical role in the circulation and persistence of antibiotic-resistant bacteria and genes, posing a significant threat to human and animal health. This article also highlights how ARGs are spread in the environment through the transfer of genetic material between bacteria. This transfer can occur naturally or through human activities such as the use of antibiotics in agriculture and waste management practices.Conclusion: It is important to integrate the One Health approach into the public health system to effectively tackle the emergence and spread of ARB and genes that code for resistance to different antibiotics.https://www.tandfonline.com/doi/10.1080/20008686.2024.2312953One healthantibiotic resistant bacteriaantibiotic resistance genes
spellingShingle Ayodele Oluwaseun Ajayi
Adebowale Toba Odeyemi
Olajide Joseph Akinjogunla
Akinwole Babafenwa Adeyeye
Ibiwumi Ayo-ajayi
Review of antibiotic-resistant bacteria and antibiotic resistance genes within the one health framework
Infection Ecology & Epidemiology
One health
antibiotic resistant bacteria
antibiotic resistance genes
title Review of antibiotic-resistant bacteria and antibiotic resistance genes within the one health framework
title_full Review of antibiotic-resistant bacteria and antibiotic resistance genes within the one health framework
title_fullStr Review of antibiotic-resistant bacteria and antibiotic resistance genes within the one health framework
title_full_unstemmed Review of antibiotic-resistant bacteria and antibiotic resistance genes within the one health framework
title_short Review of antibiotic-resistant bacteria and antibiotic resistance genes within the one health framework
title_sort review of antibiotic resistant bacteria and antibiotic resistance genes within the one health framework
topic One health
antibiotic resistant bacteria
antibiotic resistance genes
url https://www.tandfonline.com/doi/10.1080/20008686.2024.2312953
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