On the Stability of Steroids upon Gamma and E-Beam Irradiation and the Protective Effect of Inert Conditions

On the Stability of Steroids upon Gamma and E-Beam Irradiation and the Protective Effect of Inert Conditions

The sterility of ophthalmic drugs is a fundamental requirement for ensuring patient safety, and as such, it is subject to stringent regulatory standards. However, significant gaps remain regarding the effect of sterilization techniques on the impurity profile and relative content of active pharmaceu...

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Bibliographic Details
Main Authors: Quinten Speleers, Anke Meyers, Homaira Rashid, Yannick Dubbelboer, Elias Vanneste, Bart Croonenborghs, Annick Gillet, Aaron DeMent, Ann Van Schepdael, Erik Haghedooren
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
Subjects:
sterilization
irradiation
stability
ophthalmic
dexamethasone
methylprednisolone
Online Access:https://www.mdpi.com/1420-3049/30/12/2605
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