An Unusual Presentation of Thyrotoxicosis: Leg Weakness and Hypokalemia in a 21-Year-Old Male
Patients with hyperthyroidism or thyrotoxicosis present with an unspecific constellation of signs or symptoms such as palpitations, tremors, weight loss, or diarrhea. In some severe cases, hyperthyroidism can predispose patients to metabolic abnormalities and arrhythmias. Thyrotoxic periodic paralys...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2021/1776538 |
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| author | Mario S. Campana Maria Riofrio Raja S. Jadav Mattan Rozenek |
| author_facet | Mario S. Campana Maria Riofrio Raja S. Jadav Mattan Rozenek |
| author_sort | Mario S. Campana |
| collection | DOAJ |
| description | Patients with hyperthyroidism or thyrotoxicosis present with an unspecific constellation of signs or symptoms such as palpitations, tremors, weight loss, or diarrhea. In some severe cases, hyperthyroidism can predispose patients to metabolic abnormalities and arrhythmias. Thyrotoxic periodic paralysis (TTP) is a rare, life-threatening complication or variant of hyperthyroidism associated with hypokalemia and muscle weakness that affects young Asian or Hispanic males between 20–40 years. TTP is reversible, and the management consists of beta-blockers, antithyroid therapy, and conservative potassium correction to prevent severe cardiovascular events such as ventricular arrhythmias with the improvement of transient muscle paralysis. We present a case of a 21-year-old Hispanic male complaining with symptoms of thyrotoxicosis, marked hypokalemia, and severe generalized muscle weakness. Physicians must be aware of this uncommon complication of thyrotoxicosis called thyrotoxic periodic paralysis (TTP) to avoid potassium overcorrection and all the endocrine associations with this pathology. |
| format | Article |
| id | doaj-art-0a89112e856c47c0a29b67dc5ff82e1c |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-0a89112e856c47c0a29b67dc5ff82e1c2025-02-03T01:08:58ZengWileyCase Reports in Endocrinology2090-65012090-651X2021-01-01202110.1155/2021/17765381776538An Unusual Presentation of Thyrotoxicosis: Leg Weakness and Hypokalemia in a 21-Year-Old MaleMario S. Campana0Maria Riofrio1Raja S. Jadav2Mattan Rozenek3St. Barnabas Hospital, Department of Internal Medicine, SBH Health System, The Bronx, NY 10457, USASt. Barnabas Hospital, Department of Internal Medicine, SBH Health System, The Bronx, NY 10457, USASt. Barnabas Hospital, Department of Internal Medicine, SBH Health System, The Bronx, NY 10457, USASt. Barnabas Hospital, Department of Internal Medicine, SBH Health System, The Bronx, NY 10457, USAPatients with hyperthyroidism or thyrotoxicosis present with an unspecific constellation of signs or symptoms such as palpitations, tremors, weight loss, or diarrhea. In some severe cases, hyperthyroidism can predispose patients to metabolic abnormalities and arrhythmias. Thyrotoxic periodic paralysis (TTP) is a rare, life-threatening complication or variant of hyperthyroidism associated with hypokalemia and muscle weakness that affects young Asian or Hispanic males between 20–40 years. TTP is reversible, and the management consists of beta-blockers, antithyroid therapy, and conservative potassium correction to prevent severe cardiovascular events such as ventricular arrhythmias with the improvement of transient muscle paralysis. We present a case of a 21-year-old Hispanic male complaining with symptoms of thyrotoxicosis, marked hypokalemia, and severe generalized muscle weakness. Physicians must be aware of this uncommon complication of thyrotoxicosis called thyrotoxic periodic paralysis (TTP) to avoid potassium overcorrection and all the endocrine associations with this pathology.http://dx.doi.org/10.1155/2021/1776538 |
| spellingShingle | Mario S. Campana Maria Riofrio Raja S. Jadav Mattan Rozenek An Unusual Presentation of Thyrotoxicosis: Leg Weakness and Hypokalemia in a 21-Year-Old Male Case Reports in Endocrinology |
| title | An Unusual Presentation of Thyrotoxicosis: Leg Weakness and Hypokalemia in a 21-Year-Old Male |
| title_full | An Unusual Presentation of Thyrotoxicosis: Leg Weakness and Hypokalemia in a 21-Year-Old Male |
| title_fullStr | An Unusual Presentation of Thyrotoxicosis: Leg Weakness and Hypokalemia in a 21-Year-Old Male |
| title_full_unstemmed | An Unusual Presentation of Thyrotoxicosis: Leg Weakness and Hypokalemia in a 21-Year-Old Male |
| title_short | An Unusual Presentation of Thyrotoxicosis: Leg Weakness and Hypokalemia in a 21-Year-Old Male |
| title_sort | unusual presentation of thyrotoxicosis leg weakness and hypokalemia in a 21 year old male |
| url | http://dx.doi.org/10.1155/2021/1776538 |
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