60 Investigating sociodemographic influence on trauma exposure and neural alterations in young adults
Objectives/Goals: This study aims to understand the prevalence of trauma in young adults and what sociodemographic factors influence trauma exposure and type of trauma. It also seeks to explore functional connectivity and neural network patterns associated with trauma by analyzing resting state m...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2025-04-01
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| Series: | Journal of Clinical and Translational Science |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2059866124007398/type/journal_article |
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| author | Abigail Bossa Claire Marino Caitlin Sharp Tanya Garg Shreya Bavdekar Mary Halvorsen Benjamin Suzrez-Jimenez |
| author_facet | Abigail Bossa Claire Marino Caitlin Sharp Tanya Garg Shreya Bavdekar Mary Halvorsen Benjamin Suzrez-Jimenez |
| author_sort | Abigail Bossa |
| collection | DOAJ |
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Objectives/Goals: This study aims to understand the prevalence of trauma in young adults and what sociodemographic factors influence trauma exposure and type of trauma. It also seeks to explore functional connectivity and neural network patterns associated with trauma by analyzing resting state magnetic resonance imaging (MRI) data. Methods/Study Population: Sociodemographic data will be analyzed from participants aged 18–25 years, such as age, gender, race, ethnicity, and highest level of education completed. Trauma exposure will be assessed based on the DSM-5 criteria of trauma through phone screenings and clinical interviews. The data will be categorized based on trauma type and statistical analyses will be conducted to explore potential sociodemographic patterns related to trauma. Additionally, resting-state MRI data will be utilized to identify potential neural correlates of trauma exposure. Results/Anticipated Results: It is anticipated that sociodemographic factors such, race and ethnicity, and highest level of school completed may influence the likelihood of experiencing traumatic events. It is predicted that in the resting-state MRI analysis that there will be altered functional connectivity in trauma exposed young adults in regions such as the amygdala, hippocampus, and prefrontal cortex since those regions are implicated in emotional regulation and stress response. Some changes may also be seen in the default mode network and salience network. Discussion/Significance of Impact: Trauma exposure can alter neural circuitry, leading to emotional processing difficulties and heightened stress response, with lasting effects on mental health and brain development. Prevention efforts and targeted treatments can be guided by identification of affected brain networks and sociodemographic factors that increase trauma risk. |
| format | Article |
| id | doaj-art-0a7bd4079f1741018bd34d8f0b149ee6 |
| institution | Kabale University |
| issn | 2059-8661 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj-art-0a7bd4079f1741018bd34d8f0b149ee62025-08-20T03:40:54ZengCambridge University PressJournal of Clinical and Translational Science2059-86612025-04-019181810.1017/cts.2024.73960 Investigating sociodemographic influence on trauma exposure and neural alterations in young adultsAbigail Bossa0Claire Marino1Caitlin Sharp2Tanya Garg3Shreya Bavdekar4Mary Halvorsen5Benjamin Suzrez-Jimenez6University of Rochester School of Medicine and DentistryUniversity of Rochester School of Medicine and DentistryUniversity of Rochester School of Medicine and DentistryUniversity of Rochester School of Medicine and DentistryUniversity of Rochester School of Medicine and DentistryUniversity of Rochester School of Medicine and DentistryUniversity of Rochester School of Medicine and Dentistry Objectives/Goals: This study aims to understand the prevalence of trauma in young adults and what sociodemographic factors influence trauma exposure and type of trauma. It also seeks to explore functional connectivity and neural network patterns associated with trauma by analyzing resting state magnetic resonance imaging (MRI) data. Methods/Study Population: Sociodemographic data will be analyzed from participants aged 18–25 years, such as age, gender, race, ethnicity, and highest level of education completed. Trauma exposure will be assessed based on the DSM-5 criteria of trauma through phone screenings and clinical interviews. The data will be categorized based on trauma type and statistical analyses will be conducted to explore potential sociodemographic patterns related to trauma. Additionally, resting-state MRI data will be utilized to identify potential neural correlates of trauma exposure. Results/Anticipated Results: It is anticipated that sociodemographic factors such, race and ethnicity, and highest level of school completed may influence the likelihood of experiencing traumatic events. It is predicted that in the resting-state MRI analysis that there will be altered functional connectivity in trauma exposed young adults in regions such as the amygdala, hippocampus, and prefrontal cortex since those regions are implicated in emotional regulation and stress response. Some changes may also be seen in the default mode network and salience network. Discussion/Significance of Impact: Trauma exposure can alter neural circuitry, leading to emotional processing difficulties and heightened stress response, with lasting effects on mental health and brain development. Prevention efforts and targeted treatments can be guided by identification of affected brain networks and sociodemographic factors that increase trauma risk.https://www.cambridge.org/core/product/identifier/S2059866124007398/type/journal_article |
| spellingShingle | Abigail Bossa Claire Marino Caitlin Sharp Tanya Garg Shreya Bavdekar Mary Halvorsen Benjamin Suzrez-Jimenez 60 Investigating sociodemographic influence on trauma exposure and neural alterations in young adults Journal of Clinical and Translational Science |
| title | 60 Investigating sociodemographic influence on trauma exposure and neural alterations in young adults |
| title_full | 60 Investigating sociodemographic influence on trauma exposure and neural alterations in young adults |
| title_fullStr | 60 Investigating sociodemographic influence on trauma exposure and neural alterations in young adults |
| title_full_unstemmed | 60 Investigating sociodemographic influence on trauma exposure and neural alterations in young adults |
| title_short | 60 Investigating sociodemographic influence on trauma exposure and neural alterations in young adults |
| title_sort | 60 investigating sociodemographic influence on trauma exposure and neural alterations in young adults |
| url | https://www.cambridge.org/core/product/identifier/S2059866124007398/type/journal_article |
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