Concomitant Drug Interactions With Non–Vitamin K Oral Anticoagulants Are Associated With Bleeding and Mortality Risk in Patients With Nonvalvular Atrial Fibrillation

Concomitant Drug Interactions With Non–Vitamin K Oral Anticoagulants Are Associated With Bleeding and Mortality Risk in Patients With Nonvalvular Atrial Fibrillation

Background Non–vitamin K oral anticoagulants prevent stroke and systemic embolism in patients with nonvalvular atrial fibrillation. However, potential drug interactions with concomitant medications may compromise their efficacy and escalate the risk of adverse effects. Methods and Results We conduct...

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Bibliographic Details
Main Authors: Chun‐Ka Wong, Yuen‐Kwun Wong, Yap‐Hang Chan, Minqing Lin, Jojo Siu‐Han Hai, Kai‐Hang Yiu, Gregory YH Lip, Kui‐Kai Lau, Hung‐Fat Tse
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
bleeding
drug interaction
mortality
nonvalvular atrial fibrillation
non–vitamin K oral anticoagulant
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.038668
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