Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the Literature
Hypothermia is a rare and poorly understood complication of Multiple Sclerosis (MS). We report on a 66-year-old patient currently with Secondary Progressive MS (SP-MS) who developed unexplained hypothermia associated with multiple hospitalisations and we review the literature on this topic. In our c...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/2768493 |
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| _version_ | 1850232568115363840 |
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| author | Francesco Berti Zeeshan Arif Cris Constantinescu Bruno Gran |
| author_facet | Francesco Berti Zeeshan Arif Cris Constantinescu Bruno Gran |
| author_sort | Francesco Berti |
| collection | DOAJ |
| description | Hypothermia is a rare and poorly understood complication of Multiple Sclerosis (MS). We report on a 66-year-old patient currently with Secondary Progressive MS (SP-MS) who developed unexplained hypothermia associated with multiple hospitalisations and we review the literature on this topic. In our case, magnetic resonance imaging (MRI) of the brain failed to highlight hypothalamic disease, but spinal MRI identified a number of spinal cord lesions. Given the incidence and clinical significance of spinal involvement in MS and the hypothermic disturbances observed in high Spinal Cord Injury (SCI), we hypothesise that upper spinal cord pathology, along with hypothalamic and brainstem dysfunctions, can contribute to hypothermia. |
| format | Article |
| id | doaj-art-0a7a27da1888458a95e5beeaeff0ccea |
| institution | OA Journals |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-0a7a27da1888458a95e5beeaeff0ccea2025-08-20T02:03:08ZengWileyCase Reports in Neurological Medicine2090-66682090-66762018-01-01201810.1155/2018/27684932768493Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the LiteratureFrancesco Berti0Zeeshan Arif1Cris Constantinescu2Bruno Gran3Division of Clinical Neuroscience, University of Nottingham School of Medicine, Nottingham, UKDivision of Clinical Neuroscience, University of Nottingham School of Medicine, Nottingham, UKDivision of Clinical Neuroscience, University of Nottingham School of Medicine, Nottingham, UKDepartment of Neurology, Nottingham University Hospitals NHS Trust, Nottingham, UKHypothermia is a rare and poorly understood complication of Multiple Sclerosis (MS). We report on a 66-year-old patient currently with Secondary Progressive MS (SP-MS) who developed unexplained hypothermia associated with multiple hospitalisations and we review the literature on this topic. In our case, magnetic resonance imaging (MRI) of the brain failed to highlight hypothalamic disease, but spinal MRI identified a number of spinal cord lesions. Given the incidence and clinical significance of spinal involvement in MS and the hypothermic disturbances observed in high Spinal Cord Injury (SCI), we hypothesise that upper spinal cord pathology, along with hypothalamic and brainstem dysfunctions, can contribute to hypothermia.http://dx.doi.org/10.1155/2018/2768493 |
| spellingShingle | Francesco Berti Zeeshan Arif Cris Constantinescu Bruno Gran Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the Literature Case Reports in Neurological Medicine |
| title | Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the Literature |
| title_full | Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the Literature |
| title_fullStr | Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the Literature |
| title_full_unstemmed | Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the Literature |
| title_short | Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the Literature |
| title_sort | hypothermia in multiple sclerosis beyond the hypothalamus a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2018/2768493 |
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