Case report: Detection and treatment of a rare submucosal gland duct adenoma of the esophagus

This article reports a rare case of esophageal submucosal gland duct adenoma (ESGDA). The patient was found to have this tumor after undergoing endoscopy in an outpatient clinic due to occasional tingling while eating. White light endoscopy revealed the tumor as a dumbbell-shaped bulge, and ultrasou...

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Main Authors: Yu Zhou, Daoxing He, Zhigang Huang, Zhaoyi Chen, Zheng Zhou, Hui Duan, Jie Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1482068/full
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author Yu Zhou
Daoxing He
Zhigang Huang
Zhaoyi Chen
Zheng Zhou
Hui Duan
Jie Xu
author_facet Yu Zhou
Daoxing He
Zhigang Huang
Zhaoyi Chen
Zheng Zhou
Hui Duan
Jie Xu
author_sort Yu Zhou
collection DOAJ
description This article reports a rare case of esophageal submucosal gland duct adenoma (ESGDA). The patient was found to have this tumor after undergoing endoscopy in an outpatient clinic due to occasional tingling while eating. White light endoscopy revealed the tumor as a dumbbell-shaped bulge, and ultrasound endoscopy revealed it as a hypoechoic mass located in the submucosal layer. The tumor was successfully resected by endoscopic mucosal dissection with no postoperative recurrence and a good prognosis. In conjunction with literature analysis, the diagnosis of ESGDA relies mainly on endoscopic and pathologic examinations, and its histologic features are highly specific. Despite the rarity of ESGDA, accurate histologic evaluation is essential to avoid misdiagnosis. Complete endoscopic resection is an effective treatment with a favorable long-term prognosis. Further studies remain necessary to reveal its pathogenesis.
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institution Kabale University
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publishDate 2025-01-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj-art-0a709b0e0dfe40709a51527b4e286bfb2025-01-16T05:10:15ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.14820681482068Case report: Detection and treatment of a rare submucosal gland duct adenoma of the esophagusYu Zhou0Daoxing He1Zhigang Huang2Zhaoyi Chen3Zheng Zhou4Hui Duan5Jie Xu6Department of Gastroenterology, Xuancheng People’s Hospital, Anhui, ChinaDepartment of Gastroenterology, Xuancheng People’s Hospital, Anhui, ChinaDepartment of Gastroenterology, Xuancheng People’s Hospital, Anhui, ChinaDepartment of Gastroenterology, Xuancheng People’s Hospital, Anhui, ChinaDepartment of Gastroenterology, Xuancheng People’s Hospital, Anhui, ChinaDepartment of Gastroenterology, Xuancheng People’s Hospital, Anhui, ChinaElectrocardiogram Room, Huai’an Third People’s Hospital, Jiangsu, ChinaThis article reports a rare case of esophageal submucosal gland duct adenoma (ESGDA). The patient was found to have this tumor after undergoing endoscopy in an outpatient clinic due to occasional tingling while eating. White light endoscopy revealed the tumor as a dumbbell-shaped bulge, and ultrasound endoscopy revealed it as a hypoechoic mass located in the submucosal layer. The tumor was successfully resected by endoscopic mucosal dissection with no postoperative recurrence and a good prognosis. In conjunction with literature analysis, the diagnosis of ESGDA relies mainly on endoscopic and pathologic examinations, and its histologic features are highly specific. Despite the rarity of ESGDA, accurate histologic evaluation is essential to avoid misdiagnosis. Complete endoscopic resection is an effective treatment with a favorable long-term prognosis. Further studies remain necessary to reveal its pathogenesis.https://www.frontiersin.org/articles/10.3389/fonc.2024.1482068/fulladenomaesophageal submucosal gland ductesophageal tumorendoscopic resectionimmunohistochemistry
spellingShingle Yu Zhou
Daoxing He
Zhigang Huang
Zhaoyi Chen
Zheng Zhou
Hui Duan
Jie Xu
Case report: Detection and treatment of a rare submucosal gland duct adenoma of the esophagus
Frontiers in Oncology
adenoma
esophageal submucosal gland duct
esophageal tumor
endoscopic resection
immunohistochemistry
title Case report: Detection and treatment of a rare submucosal gland duct adenoma of the esophagus
title_full Case report: Detection and treatment of a rare submucosal gland duct adenoma of the esophagus
title_fullStr Case report: Detection and treatment of a rare submucosal gland duct adenoma of the esophagus
title_full_unstemmed Case report: Detection and treatment of a rare submucosal gland duct adenoma of the esophagus
title_short Case report: Detection and treatment of a rare submucosal gland duct adenoma of the esophagus
title_sort case report detection and treatment of a rare submucosal gland duct adenoma of the esophagus
topic adenoma
esophageal submucosal gland duct
esophageal tumor
endoscopic resection
immunohistochemistry
url https://www.frontiersin.org/articles/10.3389/fonc.2024.1482068/full
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