The Role of Freehand Transperineal Prostate Biopsy Under Local Anesthesia Without Antibiotics in Outpatient Settings

The objectives of this study were to evaluate and compare the application of freehand transperineal prostate biopsy (FTPB) under local anesthesia (LA) versus systematic transperineal prostate biopsy (STPB) in an outpatient setting without antibiotics. A total of 218 biopsy-naive patients with suspic...

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Main Authors: Gonglin Tang, Rui Yang, Jianing Sun, Feng Zhang, Jitao Wu, Hongwei Zhao
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:American Journal of Men's Health
Online Access:https://doi.org/10.1177/15579883241302045
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author Gonglin Tang
Rui Yang
Jianing Sun
Feng Zhang
Jitao Wu
Hongwei Zhao
author_facet Gonglin Tang
Rui Yang
Jianing Sun
Feng Zhang
Jitao Wu
Hongwei Zhao
author_sort Gonglin Tang
collection DOAJ
description The objectives of this study were to evaluate and compare the application of freehand transperineal prostate biopsy (FTPB) under local anesthesia (LA) versus systematic transperineal prostate biopsy (STPB) in an outpatient setting without antibiotics. A total of 218 biopsy-naive patients with suspicion of prostate cancer (PCa) based on multiparametric magnetic resonance imaging (mpMRI) were retrospectively analyzed. Suspicious areas on mpMRI were graded using the Prostate Imaging Reporting and Data System version 2.1 (PI-RADS v2.1). FTPB was performed for each suspicious lesion, followed by a 12-core STPB under LA. Histopathological outcomes, complications, and tolerability were recorded. The results showed that PCa was detected in 129 (59.17%) patients, with 104 (47.71%) being clinically significant prostate cancer (csPCa). There was agreement between FTPB and STPB in 94 (72.88%) patients. FTPB diagnosed fewer PCa cases but more csPCa cases than STPB. LA-FTPB was well-tolerated with no severe complications. The conclusions suggest that FTPB under LA in an outpatient setting without antibiotics is safe, feasible, and efficient.
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spelling doaj-art-0a6a813abdcd42969dec3df6b791d9062025-08-20T02:38:58ZengSAGE PublishingAmerican Journal of Men's Health1557-98912024-12-011810.1177/15579883241302045The Role of Freehand Transperineal Prostate Biopsy Under Local Anesthesia Without Antibiotics in Outpatient SettingsGonglin Tang0Rui Yang1Jianing Sun2Feng Zhang3Jitao Wu4Hongwei Zhao5Department of Urology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, ChinaDepartment of Critical Care Medicine, Shengli Oilfield Central Hospital, Dongying, ChinaSchool of Clinical Medicine, Shandong Second Medical University, Weifang, ChinaDepartment of Urology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, ChinaDepartment of Urology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, ChinaDepartment of Urology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, ChinaThe objectives of this study were to evaluate and compare the application of freehand transperineal prostate biopsy (FTPB) under local anesthesia (LA) versus systematic transperineal prostate biopsy (STPB) in an outpatient setting without antibiotics. A total of 218 biopsy-naive patients with suspicion of prostate cancer (PCa) based on multiparametric magnetic resonance imaging (mpMRI) were retrospectively analyzed. Suspicious areas on mpMRI were graded using the Prostate Imaging Reporting and Data System version 2.1 (PI-RADS v2.1). FTPB was performed for each suspicious lesion, followed by a 12-core STPB under LA. Histopathological outcomes, complications, and tolerability were recorded. The results showed that PCa was detected in 129 (59.17%) patients, with 104 (47.71%) being clinically significant prostate cancer (csPCa). There was agreement between FTPB and STPB in 94 (72.88%) patients. FTPB diagnosed fewer PCa cases but more csPCa cases than STPB. LA-FTPB was well-tolerated with no severe complications. The conclusions suggest that FTPB under LA in an outpatient setting without antibiotics is safe, feasible, and efficient.https://doi.org/10.1177/15579883241302045
spellingShingle Gonglin Tang
Rui Yang
Jianing Sun
Feng Zhang
Jitao Wu
Hongwei Zhao
The Role of Freehand Transperineal Prostate Biopsy Under Local Anesthesia Without Antibiotics in Outpatient Settings
American Journal of Men's Health
title The Role of Freehand Transperineal Prostate Biopsy Under Local Anesthesia Without Antibiotics in Outpatient Settings
title_full The Role of Freehand Transperineal Prostate Biopsy Under Local Anesthesia Without Antibiotics in Outpatient Settings
title_fullStr The Role of Freehand Transperineal Prostate Biopsy Under Local Anesthesia Without Antibiotics in Outpatient Settings
title_full_unstemmed The Role of Freehand Transperineal Prostate Biopsy Under Local Anesthesia Without Antibiotics in Outpatient Settings
title_short The Role of Freehand Transperineal Prostate Biopsy Under Local Anesthesia Without Antibiotics in Outpatient Settings
title_sort role of freehand transperineal prostate biopsy under local anesthesia without antibiotics in outpatient settings
url https://doi.org/10.1177/15579883241302045
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