Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients

Heyde’s syndrome is one of the causes of gastrointestinal bleeding in patients with heart disease. It is characterized by the acquired destruction of high molecular weight multimers of von Willebrand factor due to high hydraulic shear stress on the aortic valve in severe stenosis, followed by gastro...

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Main Authors: D. V. Belov, D. V. Garbuzenko, O. P. Lukin, S. S. Anufrieva
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2021-02-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/2503
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author D. V. Belov
D. V. Garbuzenko
O. P. Lukin
S. S. Anufrieva
author_facet D. V. Belov
D. V. Garbuzenko
O. P. Lukin
S. S. Anufrieva
author_sort D. V. Belov
collection DOAJ
description Heyde’s syndrome is one of the causes of gastrointestinal bleeding in patients with heart disease. It is characterized by the acquired destruction of high molecular weight multimers of von Willebrand factor due to high hydraulic shear stress on the aortic valve in severe stenosis, followed by gastrointestinal bleeding due to angiodysplasias. Management of such patients is a complex and relevant problem. The central method of treatment for Heyde’s syndrome is aortic valve replacement, which reduces the risk of recurrent gastrointestinal bleeding in more than 90% of patients.
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institution DOAJ
issn 1728-8800
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language Russian
publishDate 2021-02-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-0a69b6227fa145db84bd5b2dfe4c51722025-08-20T02:59:14Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252021-02-0120110.15829/1728-8800-2021-25032196Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patientsD. V. Belov0D. V. Garbuzenko1O. P. Lukin2S. S. Anufrieva3Federal Center for Cardiovascular Surgery; South Ural State Medical UniversitySouth Ural State Medical UniversityFederal Center for Cardiovascular Surgery; South Ural State Medical UniversitySouth Ural State Medical UniversityHeyde’s syndrome is one of the causes of gastrointestinal bleeding in patients with heart disease. It is characterized by the acquired destruction of high molecular weight multimers of von Willebrand factor due to high hydraulic shear stress on the aortic valve in severe stenosis, followed by gastrointestinal bleeding due to angiodysplasias. Management of such patients is a complex and relevant problem. The central method of treatment for Heyde’s syndrome is aortic valve replacement, which reduces the risk of recurrent gastrointestinal bleeding in more than 90% of patients.https://cardiovascular.elpub.ru/jour/article/view/2503heyde’s syndromeaortic stenosisgastrointestinal bleeding
spellingShingle D. V. Belov
D. V. Garbuzenko
O. P. Lukin
S. S. Anufrieva
Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients
Кардиоваскулярная терапия и профилактика
heyde’s syndrome
aortic stenosis
gastrointestinal bleeding
title Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients
title_full Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients
title_fullStr Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients
title_full_unstemmed Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients
title_short Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients
title_sort heyde s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients
topic heyde’s syndrome
aortic stenosis
gastrointestinal bleeding
url https://cardiovascular.elpub.ru/jour/article/view/2503
work_keys_str_mv AT dvbelov heydessyndromeasararecauseofgastrointestinalbleedinginaorticstenosispatients
AT dvgarbuzenko heydessyndromeasararecauseofgastrointestinalbleedinginaorticstenosispatients
AT oplukin heydessyndromeasararecauseofgastrointestinalbleedinginaorticstenosispatients
AT ssanufrieva heydessyndromeasararecauseofgastrointestinalbleedinginaorticstenosispatients