Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy
Objectives. To evaluate risk factors and to develop a simple scoring system to grade the risk of postoperative hypothyroidism (PH). Methods. In a controlled prospective study, 109 patients, who underwent hemithyroidectomy for a benign thyroid disease, were followed up for 12 months. The relation bet...
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Format: | Article |
Language: | English |
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Wiley
2015-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2015/313971 |
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author | Virgilijus Beisa Darius Kazanavicius Arminas Skrebunas Gintaras Simutis Justinas Ivaska Kestutis Strupas |
author_facet | Virgilijus Beisa Darius Kazanavicius Arminas Skrebunas Gintaras Simutis Justinas Ivaska Kestutis Strupas |
author_sort | Virgilijus Beisa |
collection | DOAJ |
description | Objectives. To evaluate risk factors and to develop a simple scoring system to grade the risk of postoperative hypothyroidism (PH). Methods. In a controlled prospective study, 109 patients, who underwent hemithyroidectomy for a benign thyroid disease, were followed up for 12 months. The relation between clinical data and PH was analyzed for significance. A risk scoring system based on significant risk factors and clinical implications was developed. Results. The significant risk factors of PH were higher TSH (thyroid-stimulating hormone) level and lower ratio of the remaining thyroid weight to the patient’s weight (derived weight index). Based on the log of risk factor, preoperative TSH level greater than 1.4 mU/L was assigned 2 points; 1 point was for 0.8–1.4 mU/L. The derived weight index lower than 0.8 g/kg was assigned 1 point. A risk scoring system was calculated by summing the scores. The incidences of PH were 7.3%, 30.4%, and 69.2% according to the risk scores of 0-1, 2, and 3. Conclusion. Risk factors for PH are higher preoperative TSH level and lower derived weight index. Our developed risk scoring system is a valid and reliable tool to identify patients who are at risk for PH before surgery. |
format | Article |
id | doaj-art-0a6852738ea541a8a9f90cb4f7dc9ba6 |
institution | Kabale University |
issn | 1687-8337 1687-8345 |
language | English |
publishDate | 2015-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Endocrinology |
spelling | doaj-art-0a6852738ea541a8a9f90cb4f7dc9ba62025-02-03T01:01:11ZengWileyInternational Journal of Endocrinology1687-83371687-83452015-01-01201510.1155/2015/313971313971Prospective Analysis of Risk for Hypothyroidism after HemithyroidectomyVirgilijus Beisa0Darius Kazanavicius1Arminas Skrebunas2Gintaras Simutis3Justinas Ivaska4Kestutis Strupas5Clinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Faculty of Medicine, Vilnius University, Santariskiu 2, LT-08661 Vilnius, LithuaniaClinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Faculty of Medicine, Vilnius University, Santariskiu 2, LT-08661 Vilnius, LithuaniaClinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Faculty of Medicine, Vilnius University, Santariskiu 2, LT-08661 Vilnius, LithuaniaClinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Faculty of Medicine, Vilnius University, Santariskiu 2, LT-08661 Vilnius, LithuaniaClinic of Ear, Nose, Throat and Eye Diseases, Center of Ear, Nose and Throat Diseases, Faculty of Medicine, Vilnius University, Santariskiu 2, LT-08661 Vilnius, LithuaniaClinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Faculty of Medicine, Vilnius University, Santariskiu 2, LT-08661 Vilnius, LithuaniaObjectives. To evaluate risk factors and to develop a simple scoring system to grade the risk of postoperative hypothyroidism (PH). Methods. In a controlled prospective study, 109 patients, who underwent hemithyroidectomy for a benign thyroid disease, were followed up for 12 months. The relation between clinical data and PH was analyzed for significance. A risk scoring system based on significant risk factors and clinical implications was developed. Results. The significant risk factors of PH were higher TSH (thyroid-stimulating hormone) level and lower ratio of the remaining thyroid weight to the patient’s weight (derived weight index). Based on the log of risk factor, preoperative TSH level greater than 1.4 mU/L was assigned 2 points; 1 point was for 0.8–1.4 mU/L. The derived weight index lower than 0.8 g/kg was assigned 1 point. A risk scoring system was calculated by summing the scores. The incidences of PH were 7.3%, 30.4%, and 69.2% according to the risk scores of 0-1, 2, and 3. Conclusion. Risk factors for PH are higher preoperative TSH level and lower derived weight index. Our developed risk scoring system is a valid and reliable tool to identify patients who are at risk for PH before surgery.http://dx.doi.org/10.1155/2015/313971 |
spellingShingle | Virgilijus Beisa Darius Kazanavicius Arminas Skrebunas Gintaras Simutis Justinas Ivaska Kestutis Strupas Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy International Journal of Endocrinology |
title | Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy |
title_full | Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy |
title_fullStr | Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy |
title_full_unstemmed | Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy |
title_short | Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy |
title_sort | prospective analysis of risk for hypothyroidism after hemithyroidectomy |
url | http://dx.doi.org/10.1155/2015/313971 |
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