Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study

Objectives To evaluate the association between caesarean section and migraine in a population-based register-linked cohort study.Setting Data from the population-based Nord-Trøndelag Health Studies (HUNT2 and HUNT3) were linked to information from the Norwegian Medical Birth Registry.Participants 65...

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Main Authors: Espen Saxhaug Kristoffersen, Knut Hagen, John-Anker Zwart, Bendik Slagsvold Winsvold, Sigrid Børte
Format: Article
Language:English
Published: BMJ Publishing Group 2020-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/11/e040685.full
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author Espen Saxhaug Kristoffersen
Knut Hagen
John-Anker Zwart
Bendik Slagsvold Winsvold
Sigrid Børte
author_facet Espen Saxhaug Kristoffersen
Knut Hagen
John-Anker Zwart
Bendik Slagsvold Winsvold
Sigrid Børte
author_sort Espen Saxhaug Kristoffersen
collection DOAJ
description Objectives To evaluate the association between caesarean section and migraine in a population-based register-linked cohort study.Setting Data from the population-based Nord-Trøndelag Health Studies (HUNT2 and HUNT3) were linked to information from the Norwegian Medical Birth Registry.Participants 65 343 participants responded to the headache questions in any of the two HUNT studies. Only those answering the headache questions in HUNT2 or 3 and had information about mode of delivery in the Norwegian Medical Birth Registry (born after 1967) were included. Our final sample consisted of 6592 women and 4602 men, aged 19–41 years.Outcomes ORs for migraine given caesarean section. Analyses were performed in multivariate logistic regression models.Results After adjusting for sex, age and fetal growth restriction, delivery by caesarean section was not associated with migraine later in life (OR 0.86, 95% CI 0.64 to 1.15). Delivery by caesarean section was associated with a reduced OR of non-migrainous headache (OR 0.77, 95% CI 0.60 to 0.99).Conclusion No association was found between caesarean section and migraine in this population-based register-linked study.
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spelling doaj-art-0a5a2eadd26745cdb61b2d11ee44f7292025-08-20T02:23:41ZengBMJ Publishing GroupBMJ Open2044-60552020-11-01101110.1136/bmjopen-2020-040685Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort studyEspen Saxhaug Kristoffersen0Knut Hagen1John-Anker Zwart2Bendik Slagsvold Winsvold3Sigrid Børte45 Department of Neurology, Akershus University Hospital, Lørenskog, NorwayClinical Research Unit Central Norway, St. Olavs University Hospital, Trondheim, Norway12 Faculty of Medicine, University of Oslo, Oslo, Norwaysenior scientist and registrar in neurologyResearch and Communication Unit for Musculoskeletal Health, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, NorwayObjectives To evaluate the association between caesarean section and migraine in a population-based register-linked cohort study.Setting Data from the population-based Nord-Trøndelag Health Studies (HUNT2 and HUNT3) were linked to information from the Norwegian Medical Birth Registry.Participants 65 343 participants responded to the headache questions in any of the two HUNT studies. Only those answering the headache questions in HUNT2 or 3 and had information about mode of delivery in the Norwegian Medical Birth Registry (born after 1967) were included. Our final sample consisted of 6592 women and 4602 men, aged 19–41 years.Outcomes ORs for migraine given caesarean section. Analyses were performed in multivariate logistic regression models.Results After adjusting for sex, age and fetal growth restriction, delivery by caesarean section was not associated with migraine later in life (OR 0.86, 95% CI 0.64 to 1.15). Delivery by caesarean section was associated with a reduced OR of non-migrainous headache (OR 0.77, 95% CI 0.60 to 0.99).Conclusion No association was found between caesarean section and migraine in this population-based register-linked study.https://bmjopen.bmj.com/content/10/11/e040685.full
spellingShingle Espen Saxhaug Kristoffersen
Knut Hagen
John-Anker Zwart
Bendik Slagsvold Winsvold
Sigrid Børte
Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study
BMJ Open
title Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study
title_full Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study
title_fullStr Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study
title_full_unstemmed Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study
title_short Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study
title_sort caesarean section and the association with migraine a retrospective register linked hunt population cohort study
url https://bmjopen.bmj.com/content/10/11/e040685.full
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