Gut health predictive indices linking gut microbiota dysbiosis with healthy state, mild gut discomfort, and inflammatory bowel disease phenotypes using gut microbiome profiling

Gut health predictive indices linking gut microbiota dysbiosis with healthy state, mild gut discomfort, and inflammatory bowel disease phenotypes using gut microbiome profiling

ABSTRACT Despite the complexity of the gut microbiome, several scores that use taxonomic characteristics exist that attempt to identify a healthy gut or gastrointestinal disease. Two systems in use are the metagenomic aerotolerant predominance index (MAPI) and keystone scores. The aim of this analys...

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Main Authors: Joann Phan, Suneer Jain, Jurgen F. Nijkamp, Rajkumar Sasidharan, Ashish Agarwal, Julia K. Bird, Anneleen Spooren, Jonas Wittwer Schegg, Emiel Ver Loren van Themaat, Tim N. Mak
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
gut microbiome
inflammatory bowel disease
gut inflammation
keystone score
metagenomic aerotolerant predominance index
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00271-25
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