Syntheses of Chiral 2-Oxazolines from Isosorbide Epoxide Derivative

Syntheses of Chiral 2-Oxazolines from Isosorbide Epoxide Derivative

Two chiral monooxazolines were synthesized from a secondary amino alcohol, as a key intermediate, isolated in four steps from an isosorbide-derived epoxide. The 2-oxazolines were then obtained through a reaction between this aminoalcohol and an imidate. The new compounds were fully characterized by...

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Bibliographic Details
Main Authors: Mohammed Kadraoui, Stéphane Guillarme, Christine Saluzzo
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Molbank
Subjects:
isosorbide
sustainable material
chiral aminoalcohol
chiral 2-oxazoline
oxirane
epoxide
Online Access:https://www.mdpi.com/1422-8599/2025/1/M1966
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