Syntheses of Chiral 2-Oxazolines from Isosorbide Epoxide Derivative
Two chiral monooxazolines were synthesized from a secondary amino alcohol, as a key intermediate, isolated in four steps from an isosorbide-derived epoxide. The 2-oxazolines were then obtained through a reaction between this aminoalcohol and an imidate. The new compounds were fully characterized by...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-02-01
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| Series: | Molbank |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-8599/2025/1/M1966 |
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| Summary: | Two chiral monooxazolines were synthesized from a secondary amino alcohol, as a key intermediate, isolated in four steps from an isosorbide-derived epoxide. The 2-oxazolines were then obtained through a reaction between this aminoalcohol and an imidate. The new compounds were fully characterized by FTIR, <sup>1</sup>H and <sup>13</sup>C NMR, and HRMS analyses. |
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| ISSN: | 1422-8599 |