HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN
The study was aimed at hemodynamic effects of xenon on operative interventions in children. Patients and methods: the study involved 30 5-17-year-old children – 10 (33.3%) girls and 20 (66.7%) boys with ASA score 1-3 admitted for surgical treatment. The children underwent endotracheal anesthesia wit...
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Union of pediatricians of Russia
2014-05-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/96 |
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| author | M. V. Bykov V. G. Bagaev V. G. Amcheslavskiy |
| author_facet | M. V. Bykov V. G. Bagaev V. G. Amcheslavskiy |
| author_sort | M. V. Bykov |
| collection | DOAJ |
| description | The study was aimed at hemodynamic effects of xenon on operative interventions in children. Patients and methods: the study involved 30 5-17-year-old children – 10 (33.3%) girls and 20 (66.7%) boys with ASA score 1-3 admitted for surgical treatment. The children underwent endotracheal anesthesia with xenon-oxygen mixture (Xe:O2 = 60-65:30%) and fentanyl (2.5‑3.5 mcg/kg per hour) for the following operations: appendectomy – 10 (33.3%) patients, herniotomy – 8 (26.7%) patients, Ivanissevich procedure – 6 (20.0%) patients, plastic surgery of posttraumatic defects of skin and soft tissues – 4 (13.3%) patients, abdominal adhesiotomy – 2 (6.7%) patients. Central hemodynamics was studied echocardiographically (Philips HD 11, the Netherlands) using the Teichholz technique along the cephalocaudal axis (parasternal access). Results: the anesthesia was notable for hemodynamic stability during the operation: as a result, a statistically significant (p < 0.05) increase in systolic, diastolic and mean arterial pressure by 10, 18 and 17%, respectively, was observed. Conclusion: the analysis demonstrated that xenon anesthesia improves lusitropic myocardial function statistically significantly increasing cardiac output by 12% by way of increasing stroke volume by 30%. |
| format | Article |
| id | doaj-art-0a3ddab2ec4a484492037f688c27e736 |
| institution | DOAJ |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2014-05-01 |
| publisher | Union of pediatricians of Russia |
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| series | Педиатрическая фармакология |
| spelling | doaj-art-0a3ddab2ec4a484492037f688c27e7362025-08-20T03:23:02ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892014-05-01113424710.15690/pf.v11i3.100796HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDRENM. V. Bykov0V. G. Bagaev1V. G. Amcheslavskiy2Research institute of pediatric surgery and traumatology, MoscowResearch Institute of Pediatric Surgery and Traumatology, Moscow, Russian FederationResearch Institute of Pediatric Surgery and Traumatology, Moscow, Russian FederationThe study was aimed at hemodynamic effects of xenon on operative interventions in children. Patients and methods: the study involved 30 5-17-year-old children – 10 (33.3%) girls and 20 (66.7%) boys with ASA score 1-3 admitted for surgical treatment. The children underwent endotracheal anesthesia with xenon-oxygen mixture (Xe:O2 = 60-65:30%) and fentanyl (2.5‑3.5 mcg/kg per hour) for the following operations: appendectomy – 10 (33.3%) patients, herniotomy – 8 (26.7%) patients, Ivanissevich procedure – 6 (20.0%) patients, plastic surgery of posttraumatic defects of skin and soft tissues – 4 (13.3%) patients, abdominal adhesiotomy – 2 (6.7%) patients. Central hemodynamics was studied echocardiographically (Philips HD 11, the Netherlands) using the Teichholz technique along the cephalocaudal axis (parasternal access). Results: the anesthesia was notable for hemodynamic stability during the operation: as a result, a statistically significant (p < 0.05) increase in systolic, diastolic and mean arterial pressure by 10, 18 and 17%, respectively, was observed. Conclusion: the analysis demonstrated that xenon anesthesia improves lusitropic myocardial function statistically significantly increasing cardiac output by 12% by way of increasing stroke volume by 30%.https://www.pedpharma.ru/jour/article/view/96xenoninhalation anesthesiahemodynamics at xenonchildren |
| spellingShingle | M. V. Bykov V. G. Bagaev V. G. Amcheslavskiy HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN Педиатрическая фармакология xenon inhalation anesthesia hemodynamics at xenon children |
| title | HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN |
| title_full | HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN |
| title_fullStr | HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN |
| title_full_unstemmed | HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN |
| title_short | HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN |
| title_sort | hemodynamic effects of xenon anesthesia in children |
| topic | xenon inhalation anesthesia hemodynamics at xenon children |
| url | https://www.pedpharma.ru/jour/article/view/96 |
| work_keys_str_mv | AT mvbykov hemodynamiceffectsofxenonanesthesiainchildren AT vgbagaev hemodynamiceffectsofxenonanesthesiainchildren AT vgamcheslavskiy hemodynamiceffectsofxenonanesthesiainchildren |