HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN
The study was aimed at hemodynamic effects of xenon on operative interventions in children. Patients and methods: the study involved 30 5-17-year-old children – 10 (33.3%) girls and 20 (66.7%) boys with ASA score 1-3 admitted for surgical treatment. The children underwent endotracheal anesthesia wit...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Union of pediatricians of Russia
2014-05-01
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| Series: | Педиатрическая фармакология |
| Subjects: | |
| Online Access: | https://www.pedpharma.ru/jour/article/view/96 |
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| Summary: | The study was aimed at hemodynamic effects of xenon on operative interventions in children. Patients and methods: the study involved 30 5-17-year-old children – 10 (33.3%) girls and 20 (66.7%) boys with ASA score 1-3 admitted for surgical treatment. The children underwent endotracheal anesthesia with xenon-oxygen mixture (Xe:O2 = 60-65:30%) and fentanyl (2.5‑3.5 mcg/kg per hour) for the following operations: appendectomy – 10 (33.3%) patients, herniotomy – 8 (26.7%) patients, Ivanissevich procedure – 6 (20.0%) patients, plastic surgery of posttraumatic defects of skin and soft tissues – 4 (13.3%) patients, abdominal adhesiotomy – 2 (6.7%) patients. Central hemodynamics was studied echocardiographically (Philips HD 11, the Netherlands) using the Teichholz technique along the cephalocaudal axis (parasternal access). Results: the anesthesia was notable for hemodynamic stability during the operation: as a result, a statistically significant (p < 0.05) increase in systolic, diastolic and mean arterial pressure by 10, 18 and 17%, respectively, was observed. Conclusion: the analysis demonstrated that xenon anesthesia improves lusitropic myocardial function statistically significantly increasing cardiac output by 12% by way of increasing stroke volume by 30%. |
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| ISSN: | 1727-5776 2500-3089 |