Acceptability of a clofazimine tablet in children with rifampicin-resistant TB in three high-burden countries

Acceptability of a clofazimine tablet in children with rifampicin-resistant TB in three high-burden countries

BACKGROUND: Rifampicin-resistant TB (RR-TB) in children is frequently treated with clofazimine (CFZ), widely available as a 100mg gel capsule. This formulation is challenging to administer and is poorly acceptable to children and caregivers. Poor acceptability may negatively impact adherence and tre...

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Bibliographic Details
Main Authors: L. Viljoen, H.R. Draper, N.T. Castillo-Carandang, N. Suryavanshi, A. Marthinus, A.M.A. Cheong, J.D.D. Ocampo, G. Dhumal, S. Bagchi, D.T. Wademan, A. Kinikar, M. Paradkar, M.V.G. Frias IV, D.J.O. Casalme, A.C. Hesseling, A.J. Garcia-Prats, M. Palmer, G. Hoddinott, on behalf of the CATALYST trial team
Format: Article
Language:English
Published: International Union Against Tuberculosis and Lung Disease (The Union) 2025-08-01
Series:IJTLD Open
Subjects:
tuberculosis
drug-resistant tb
dispersible tablets
south africa
india
philippines
Online Access:https://www.ingentaconnect.com/contentone/iuatld/ijtldo/2025/00000002/00000008/art00006
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