A man who changed six spectacles: а case of Heidenhain variant of the Creutzfeldt–Jakob disease
Creutzfeldt–Jakob Disease (CJD) is a rare and rapidly progressive condition. A 54-year-old professor initially presented with insidious, progressive visual symptoms. Imaging suggested post-infectious encephalitis, but symptoms progressed to ataxia, coordination difficulties, and cognitive decline. R...
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| Format: | Article |
| Language: | English |
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Research Center of Neurology
2024-07-01
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| Series: | Анналы клинической и экспериментальной неврологии |
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| Online Access: | https://annaly-nevrologii.com/journal/pathID/article/viewFile/977/pdf |
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| author | Ishwarya Thiruvuru Philo Hazeena Rithvik Ramesh Sundar Shanmugam Deepa Avadhani |
| author_facet | Ishwarya Thiruvuru Philo Hazeena Rithvik Ramesh Sundar Shanmugam Deepa Avadhani |
| author_sort | Ishwarya Thiruvuru |
| collection | DOAJ |
| description | Creutzfeldt–Jakob Disease (CJD) is a rare and rapidly progressive condition. A 54-year-old professor initially presented with insidious, progressive visual symptoms. Imaging suggested post-infectious encephalitis, but symptoms progressed to ataxia, coordination difficulties, and cognitive decline. Repeat MRI revealed findings consistent with CJD, supported by clinical and electrophysiological evidence. Though 14-3-3 protein in CSF was inconclusive, Heidenhain variant CJD was strongly suspected. Isolated visual symptoms progressing rapidly alongside ataxia and dementia prompt suspicion of this variant. Clinical examination, neuroimaging, and EEG play crucial roles in the diagnosis. |
| format | Article |
| id | doaj-art-0a2f910bbc6140c8a526c21a4448968e |
| institution | OA Journals |
| issn | 2075-5473 2409-2533 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Research Center of Neurology |
| record_format | Article |
| series | Анналы клинической и экспериментальной неврологии |
| spelling | doaj-art-0a2f910bbc6140c8a526c21a4448968e2025-08-20T02:13:01ZengResearch Center of NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-25332024-07-01182959910.17816/ACEN.977686A man who changed six spectacles: а case of Heidenhain variant of the Creutzfeldt–Jakob diseaseIshwarya Thiruvuru0https://orcid.org/0009-0003-7261-5151Philo Hazeena1https://orcid.org/0000-0001-6221-431XRithvik Ramesh2https://orcid.org/0000-0002-4142-637XSundar Shanmugam3https://orcid.org/0000-0002-6580-9017Deepa Avadhani4https://orcid.org/0009-0004-0991-9563Sri Ramachandra Institute of Higher Education and ResearchSri Ramachandra Institute of Higher Education and ResearchSri Ramachandra Institute of Higher Education and ResearchSri Ramachandra Institute of Higher Education and ResearchSri Ramachandra Institute of Higher Education and ResearchCreutzfeldt–Jakob Disease (CJD) is a rare and rapidly progressive condition. A 54-year-old professor initially presented with insidious, progressive visual symptoms. Imaging suggested post-infectious encephalitis, but symptoms progressed to ataxia, coordination difficulties, and cognitive decline. Repeat MRI revealed findings consistent with CJD, supported by clinical and electrophysiological evidence. Though 14-3-3 protein in CSF was inconclusive, Heidenhain variant CJD was strongly suspected. Isolated visual symptoms progressing rapidly alongside ataxia and dementia prompt suspicion of this variant. Clinical examination, neuroimaging, and EEG play crucial roles in the diagnosis.https://annaly-nevrologii.com/journal/pathID/article/viewFile/977/pdfcreutzfeldt–jacob diseaseheidenhain variant |
| spellingShingle | Ishwarya Thiruvuru Philo Hazeena Rithvik Ramesh Sundar Shanmugam Deepa Avadhani A man who changed six spectacles: а case of Heidenhain variant of the Creutzfeldt–Jakob disease Анналы клинической и экспериментальной неврологии creutzfeldt–jacob disease heidenhain variant |
| title | A man who changed six spectacles: а case of Heidenhain variant of the Creutzfeldt–Jakob disease |
| title_full | A man who changed six spectacles: а case of Heidenhain variant of the Creutzfeldt–Jakob disease |
| title_fullStr | A man who changed six spectacles: а case of Heidenhain variant of the Creutzfeldt–Jakob disease |
| title_full_unstemmed | A man who changed six spectacles: а case of Heidenhain variant of the Creutzfeldt–Jakob disease |
| title_short | A man who changed six spectacles: а case of Heidenhain variant of the Creutzfeldt–Jakob disease |
| title_sort | man who changed six spectacles а case of heidenhain variant of the creutzfeldt jakob disease |
| topic | creutzfeldt–jacob disease heidenhain variant |
| url | https://annaly-nevrologii.com/journal/pathID/article/viewFile/977/pdf |
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