TGF-β/Smad2/3 signaling directly regulates several miRNAs in mouse ES cells and early embryos.

TGF-β/Smad2/3 signaling directly regulates several miRNAs in mouse ES cells and early embryos.

The Transforming Growth Factor-β (TGF-β) signaling pathway is one of the major pathways essential for normal embryonic development and tissue homeostasis, with anti-tumor but also pro-metastatic properties in cancer. This pathway directly regulates several target genes that mediate its downstream fu...

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Bibliographic Details
Main Authors: Nicholas Redshaw, Carme Camps, Vikas Sharma, Mehdi Motallebipour, Marcela Guzman-Ayala, Spyros Oikonomopoulos, Efstathia Thymiakou, Jiannis Ragoussis, Vasso Episkopou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0055186&type=printable
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