Punicic acid alleviates methylglyoxal-induced oocyte dysfunction during in vitro maturation in mouse species.

Punicic acid alleviates methylglyoxal-induced oocyte dysfunction during in vitro maturation in mouse species.

Dicarbonyl stress, characterized by the abnormal accumulation of reactive dicarbonyl metabolites and advanced glycation end-products (AGEs), is implicated in various pathological conditions, including obesity, diabetes, and reproductive disorders. Methylglyoxal (MGO), a highly reactive dicarbonyl me...

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Main Authors: Shahrzad Ronasi, Amir Hossein Mahdavi, Shiva Rouhollahi Varnosfaderani, Rasoul Kowsar, Farnoosh Jafarpour, Mohammad Hossein Nasr-Esfahani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0314602
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